A single dose of 20 mg intravenous HBB is effective and safe in shortening the duration of the first stage of labor without any adverse effects on fetus and mother.

PURPOSE:To investigate whether chitosan application over colonic anastomosis line, provide reinforcement, and subsequently improve anastomotic healing. METHODS:Forty eight Wistar albino female rats were used and were randomly divided into four groups, 12 rats in each: The control groups (1 and 3) received no further treatment. The experimental groups (2 and 4) received chitosan application over the colonic anastomosis. After sacrifying rats at the end of the experiment (either on day three or on day seven, depending on the group), colonic bursting pressure, a hihydroxyproline level and histopathologic characteristics of the perianastomotic tissue were examined. RESULTS:At three days, chitosan and control groups had similar values for histopathologically. On day seven, chitosan group had significantly higher mean score of collagenization (p=0.007) and a significantly higher bursting pressure (p=0.038). CONCLUSION:Our study emphasizes the positive effect of chitosan in the process of collagenation in colonic anastomosis healing. Key words: Chitosan. Anastomosis, Surgical. Tensile Strength. Wound Healing. Rats. RESUMO OBJETIVO:Investigar se a aplicação de quitosana em anastomose colônica promove resistência à tração e consequentemente a melhora na cicatrização. MÉTODOS:Foram utilizados 48 ratos Wistar fêmeas distribuídos em quatro grupos, 12 ratos em cada. Grupos controle (1 e 3) não receberam tratamento. Grupos experimento (2 e 4) receberam aplicação de quitosana na anastomose colônica. Após eutanásia após 3º ou 7º dias foram examinadas a tensão, o nível de hidroxiprolina e aspectos histopatológicos da anastomose. RESULTADOS:Após três dias os grupos controle e quitosana não apresentaram alterações histopatológicas. No sétimo dia o grupo quitosana apresentou significante elevação do escore de colagenização (p=0,007) e da tensão de ruptura (p=0,038). CONCLUSÃO:A quitosana apresentou bons resultados nos processos de colagenização e cicatrização de anastomose colônica.Descritores: Quitosana. Anastomose Cirúrgica. Resistência à Tração. Cicatrização. Ratos.Citgez B et al.

The aim of this study is to compare the diagnostic accuracy of transvaginal ultrasonography and hysteroscopy in the detection of intracavitary abnormalities that presented with abnormal uterine bleeding. Material and Methods: 216 women with uterine bleeding involve in this study. In this retrospective study, the diagnostic accuracy of transvaginal ultrasonography and hysteroscopy were compared to their corresponding pathology results in both prepostmenopausal (n:145) and postmenopausal (n:71) women. To compare these three methods more reliably, we used Kappa analyses. Results: In postmenopausal group with endometrial polyp and myomas; sensitivity of transvaginal ultrasonography is 68.2% to 40% dilatation & curettage, specificity is 33.3% to 97% and Kappa value is 0.016 to 0.407. Sensitivity of hysteroscopy is 97.7% to 40% dilatation & curettage, specificity is 74.1% to 100% and Kappa values is 0.75 to 0.553. Specificity of transvaginal ultrasonography is 98.3% to hysteroscopy, specificity of transvaginal ultrasonography is 98.1% to dilatation & curettage, sensitivity of hysteroscopy is 47.1% and specificity is 90.7% to dilatation & curettage and Kappa value is 0.411 with normal patients in the same group. Conclusion: In postmenopausal patients transvaginal ultrasonography has a high chance of detecting when there is an endometrial pathology. Transvaginal ultrasonography is not sensitive enough to use solely in order to exclude polyps and fibroids in abnormal uterin bleeding. Therefore, hysteroscopy can be applied even if transvaginal ultrasonography is normal in these patients.