Most of the crop salt tolerance studies are often conducted in a glasshouse and are limited under field conditions. Therefore, a field experiment was conducted under normal and salt-affected soil conditions during 2018/2019 and 2019/2020 seasons at Experimental Farm of Sakha Agricultural Research Station, Agricultural Research Center, Giza, Egypt, to authenticate the performance of physiological and agronomical characters of some Egyptian wheat genotypes. Each soil type was done in separate experiment. Every experiment of soil type was carried out in randomized complete blocks design with three replications, where each experiment incorporated eighteen wheat genotypes. Combined analysis was done between soil types and seasons. Cultivating wheat genotypes under normal soil conditions significantly increased all studied physiological and agronomical characters of wheat and gave the highest values in both seasons and its combined. Sakha95 cultivar exceeded followed by Misr3 cultivar over the other studied wheat genotypes in chlorophyll a, b, total chlorophyll contents, number of spikes/m 2 , 1000-grain weight and grain yield/fed and recorded the highest values of these characters as combined over both seasons. It could notable that cultivating wheat Sakha95 cultivar under normal soil conditions produced the highest physiological and agronomical characters. Under salt-affected soil, Misr1 then Shandaweel1 cultivars produced the highest characteristics. Besides, the highest salinity tolerance of investigated wheat genotypes was Sakha95 cultivar, followed by Sids13 cultivar, then Misr3 cultivar, Sids14 cultivar and (SPL2018)#3 line according to stress susceptibility index (SSI) results under the environmental conditions of Sakha district,
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