IntroductionExisting mobility endpoints based on functional performance, physical assessments and patient self-reporting are often affected by lack of sensitivity, limiting their utility in clinical practice. Wearable devices including inertial measurement units (IMUs) can overcome these limitations by quantifying digital mobility outcomes (DMOs) both during supervised structured assessments and in real-world conditions. The validity of IMU-based methods in the real-world, however, is still limited in patient populations. Rigorous validation procedures should cover the device metrological verification, the validation of the algorithms for the DMOs computation specifically for the population of interest and in daily life situations, and the users’ perspective on the device.Methods and analysisThis protocol was designed to establish the technical validity and patient acceptability of the approach used to quantify digital mobility in the real world by Mobilise-D, a consortium funded by the European Union (EU) as part of the Innovative Medicine Initiative, aiming at fostering regulatory approval and clinical adoption of DMOs.After defining the procedures for the metrological verification of an IMU-based device, the experimental procedures for the validation of algorithms used to calculate the DMOs are presented. These include laboratory and real-world assessment in 120 participants from five groups: healthy older adults; chronic obstructive pulmonary disease, Parkinson’s disease, multiple sclerosis, proximal femoral fracture and congestive heart failure. DMOs extracted from the monitoring device will be compared with those from different reference systems, chosen according to the contexts of observation. Questionnaires and interviews will evaluate the users’ perspective on the deployed technology and relevance of the mobility assessment.Ethics and disseminationThe study has been granted ethics approval by the centre’s committees (London—Bloomsbury Research Ethics committee; Helsinki Committee, Tel Aviv Sourasky Medical Centre; Medical Faculties of The University of Tübingen and of the University of Kiel). Data and algorithms will be made publicly available.Trial registration numberISRCTN (12246987).
We introduce ReDites, a system for realtime event detection, tracking, monitoring and visualisation. It is designed to assist Information Analysts in understanding and exploring complex events as they unfold in the world. Events are automatically detected from the Twitter stream. Then those that are categorised as being security-relevant are tracked, geolocated, summarised and visualised for the end-user. Furthermore, the system tracks changes in emotions over events, signalling possible flashpoints or abatement. We demonstrate the capabilities of ReDites using an extended use case from the September 2013 Westgate shooting incident. Through an evaluation of system latencies, we also show that enriched events are made available for users to explore within seconds of that event occurring.
Comparative evaluation of Machine Learning (ML) systems used for Information Extraction (IE) has suffered from various inconsistencies in experimental procedures. This paper reports on the results of the Pascal Challenge on Evaluating Machine Learning for Information Extraction, which provides a standardised corpus, set of tasks, and evaluation methodology. The challenge is described and the systems submitted by the ten participants are briefly introduced and their performance is analysed.
We survey the evaluation methodology adopted in information extraction (IE), as defined in a few different efforts applying machine learning (ML) to IE. We identify a number of critical issues that hamper comparison of the results obtained by different researchers. Some of these issues are common to other NLP-related tasks: e.g., the difficulty of exactly identifying the effects on performance of the data (sample selection and sample size), of the domain theory (features selected), and of algorithm parameter settings. Some issues are specific to IE: how leniently to assess inexact identification of filler boundaries, the possibility of multiple fillers for a slot, and how the counting is performed. We argue that, when specifying an IE task, these issues should be explicitly addressed, and a number of methodological characteristics should be clearly defined. To empirically verify the practical impact of the issues mentioned above, we perform a survey of the results of different algorithms when applied to a few standard datasets. The survey shows a serious lack of consensus on these issues, which makes it difficult to draw firm conclusions on a comparative evaluation of the algorithms. Our aim is to elaborate a clear and detailed experimental methodology and propose it to the IE community. Widespread agreement on this proposal should lead to future IE comparative evaluations that are fair and reliable. To demonstrate the way the methodology is to be applied we have organized and run a comparative evaluation of ML-based IE systems (the Pascal Challenge on ML-based IE) where the principles described in this article are put into practice. In this article we describe the proposed methodology and its motivations. The Pascal evaluation is then described and its results presented.
Abstract. The requirement for anthropocentric, or human-centred decision support is outlined, and the IDIOMS management information tool, which implements several human-centred principles, is described. IDIOMS provides a flexible decision support environment in which applications can be modelled using both 'objective' database information, and user-centred 'subjective' and contextual information. The system has been tested on several real applications, demonstrating its power and flexibility.
Availability and access to information is critical for a highly effective response to an ongoing event however, information reported by citizens is based on their context, bias and subjective interpretation, and the channel of communication may be too narrow to provide clear, accurate reporting. This can often lead to inadequate response to an emergency, which can in turn result in loss of property or even lives. Excessive response to an emergency can also result in a waste of highly resources. The authors' solution to address this problem is to make the citizen act as a camera for the control room by exploiting the user's mobile camera. The system is designed to provide a live view of the citizen's immediate surroundings, while control room personnel can provide instructions. In this paper, the authors introduce their approach and share initial insights from a focus group validation session and then four evaluations with users within a separate but closely related domain. They discuss their observations, evaluation results and provide a set of recommendations for the Emergency Response domain.
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