Green synthesis has attracted significant attention as an eco-friendly, low-cost, energy-efficient, and non-toxic method for preparing silver nanoparticles (AgNPs) for cancer therapy. This study optimized the green synthesis of AgNPs using Olea europaea extracts and evaluated their anticancer potential. The biosynthesized AgNPs were characterized using various methods, showing stable AgNPs with a desirable morphology and high yield, improving the properties of AgNPs for various medicinal applications. The biosynthesized AgNPs were predominantly spherical, with small sizes ranging from 13 to 21 nm and highly stable at −23 and −24 mV. The findings of this study suggest that green-synthesized AgNPs using Olea europaea and sunlight possess significant anticancer activity against cancer cells in vitro. Further investigation of green synthesis would help to form high-quality AgNPs that have promising potential in treating disease and fighting undesirable pathogens.
Silver nanoparticles (AgNPs) have been considered promising candidates for medical practices in various fields. This study proposed an efficient, economical, uncomplicated, and reliable method to synthesize AgNPs utilizing leaf and fruit extracts of Juniperus procera (J. procera)
as capping, reducing, and stabilizing agents. The study includes optimizing the green synthesis conditions to produce stable AgNPs with high yields, acceptable particle size, and shape, hence, AgNPs may be used for different medical purposes through the improvement of their properties. Several
spectroscopic and other analyses performed characterization of the fabricated AgNPs, and the results show stable and spherical AgNPs between 14 and 18 nm in size. The study also evaluated the anticancer activities of the biosynthesized AgNPs using J. procera fruit and leaf extracts
against in vitro lung cancer A549 and H1975 cells. The results demonstrate the high toxicity of the biosynthesized AgNPs against in vitro lung cancer cells, supporting therapeutic and biomedical applications of AgNPs.
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