BACKGROUNDSuperficial dermatophytosis is a common clinical entity in tropical countries like India. Limited tinea corporis and cruris can be managed by topical antifungals. Amorolfine is a much less studied antifungal compared to others. Aim-To compare the efficacy of once a day versus twice daily application of amorolfine 0.25% cream. MATERIALS AND METHODSAll new patients having limited tinea corporis and tinea cruris with KOH positivity were recruited in the study. Patients were randomly grouped as once a day application (Group A) and twice a day application (Group B). Study duration was 6 weeks, first visit after 3 weeks (end of the treatment phase) and second visit after 6 weeks (end of followup). During each visit, patients were examined, asked about the side effects, global response was noted, KOH scraping and clinical photographs were taken. RESULTSA total of 82 patients were recruited in the study, 12 patients lost to followup. Sixty patients completed the study, 30 in each group. Demographics were comparable in each group. At the end of the study, 80% patients in group A and 90% in group B got total clearance which was not significant. CONCLUSIONTwice a day application of amorolfine is more effective than once a day.
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