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The International Molecular Exchange (IMEx) Consortium provides scientists with a single body of experimentally verified protein interactions curated in rich contextual detail to an internationally agreed standard. In this update to the work of the IMEx Consortium, we discuss how this initiative has been working in practice, how it has ensured database sustainability, and how it is meeting emerging annotation challenges through the introduction of new interactor types and data formats. Additionally, we provide examples of how IMEx data are being used by biomedical researchers and integrated in other bioinformatic tools and resources.

Background: Burns are the second most common etiology of injury death in children under 5 years old and are the most common cause of death in a home accident. Materials & Methods: This study was performed to investigate the epidemiology of childhood burn in children under 16 years old referred to Velayat Burn Center, Rasht City, Iran, from 2013 to 2018. Data were collected from electronic hospital records of burn patients aged under 16 years of age. Results: Out of 717 patients, 44.5% were girls, and 55.5% were boys (sex ratio=1.2). The highest frequency of burns (56.1%) was reported in the 1-5 years age group. The most common cause of burn was scalds (76%), and the most common burn severity was second-degree burns (46.7%). The Mean±SD duration of hospitalization was 3.07±4.15 days, and the hospital stay was significantly associated with the cause of the burn, Burned Body Surface Area (BBSA), and burn severity. The highest frequency was reported on Saturdays, i.e., (the first working day in Iran) (22.7%), between 6 and 12 o’clock (42.8%). Conclusion: This study found that children in 1-5 years old were the most susceptible age group for burn injuries and scalds were the most common cause of the burn. The male to female ratio was 1.2, and the majority of burns occurred in the winter.

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