Rats were given MnCl2.4H2O (8 mg/kg) intraperitoneally daily for 120 days, and then sacrificed by decapitation. The brain was removed and dissected into three regions; cerebral cortex, cerebellum and remainder of the brain. Enzymic studies were conducted in these regions and compared with control animals. The activities of acetyl choline esterase and adenosine deaminase were significantly reduced in all the three regions. The activity of monoamine oxidase was increased in the cerebellum while the activity of guanine deaminase decreased in the cerebellum and remainder of the brain. The analysis of the results allows no overall generalization in enzymic alterations induced by manganese chloride in the three regions of the rat brain.
VLM is a zoonotic disease caused by the migration of third-stage larvae of nematodes through the tissue of human viscera. Among various etiological agents such as Baylisascaris procyonis, Capillaria hepatica, Ascaris sum, and some Ancylostoma species, Toxocara is a major cause of VLM. Poor hygiene, contact with dogs and geophagia increases the risk of toxocariasis.Young adults and children who are in close contact with animals are at a higher risk. Here we present a case of 7 years male child presenting with fever, abdominal pain and vomiting. The clinical presentation, biochemical and radiological findings supported the diagnosis of VLM which was corroborated in the cytological examination. Here we report a rarest encounter of VLM in the cytology smear.
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