The biomolecules offer different metal-binding sites to form a coordination polymer with structural diversity. The coordination directed one-dimensional metal-biomolecule nanofibers (Cu-Asp NFs) designed using copper as metal ion and aspartate as a ligand for triboelectric nanogenerator (TENG) is reported here. The different characterization techniques reveal the detailed characteristics of the synthesized Cu-Asp NFs. The robust coating of the Cu-Asp NFs is achieved using a simple tape cast coater. The bending and water dipping studies suggest the stability of the coated material. The relative polarity test and Kelvin probe force microscopy (KPFM) reveal the position of Cu-Asp in the triboelectric series. The Cu-Asp NFs and Teflon are used as the active material for the fabrication of freestanding mode (NF-TENG) and contact-separation mode (cNF-TENG) TENG. The NF-TENG generates an output of 200 V and 6 μA. The simple ion deposition technique enhances the voltage, current, and transferred charge of cNF-TENG by 2.5, 8, and 3 times. The use of the material for the single electrode sliding mode device further confirms the coated material's stability and robustness. A selective selfpowered thioacetamide sensor is developed with the cNF-TENG, which exhibits a sensitivity of 0.76 v mM −1 . Finally, NF-TENG is demonstrated for powering up numerous portable electronics.
Considering
the public health demands for stronger and effective
personal protective clothing, herein, antimicrobial fabrics using
a known bacteriostatic and fungistatic drug zinc pyrithione (ZPT)
have been reported. ZPT was synthesized in situ on
cellulosic fabric, viscose (VC), using a zinc metal precursor and
2-mercaptopyridine-N-oxide as a ligand (VC-ZPT).
For comparison, viscose was also phosphorylated (VP) before in situ functionalization with ZPT (VP-ZPT). Both approaches
provided adequate protection from microbes; however, functionalization
of cellulose with phosphate (VP) resulted in the formation of a linking
group between cellulose and ZPT, which exhibited better uniformity
of ZPT over the fabric surface and higher durability to washing. The
functionalization was confirmed by inductively coupled plasma mass
spectroscopy (ICP-MS), scanning electron microscopy (SEM), and Raman
spectroscopy. Further, the bonding of phosphate with ZPT was confirmed
by 31P solid-state NMR. The physical properties, such as
appearance, bending length, and mechanical strength, of the treated
fabrics remained unchanged. The antimicrobial activities of VP-ZPT
with VC-ZPT were studied against Escherichia coli, Staphylococcus aureus, and Candida albicans, which were found to be effective
until 20 laundry cycles in VP-ZPT. Additionally, VP-ZPT samples exhibited
poor adherence of bacteria on the fabric surface. The functionalized
fabrics may find applications for topical skin diseases in reducing
the necessity of repeated use of antibiotic ointments.
Chiral 4,4–dimethyl tetrahydrofuran (THF) derivatives were synthesized from commercially available D‐(–)/ l‐(+) pantolactones, which can serve as chiral building blocks in medicinal chemistry. In addition, two of the synthesized building blocks were utilized for the synthesis of new amprenavir (HIV protease inhibitor) and empagliflozin (anti‐diabetic) analogs. The synthesized analogs may have beneficial effects in terms of pharmacokinetics and modulation of bioactivity.
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