This study reveals that niosomes can be an efficient delivery system for the treatment of gout.

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The pandemic of coronavirus infection 2019 (COVID-19) due to the serious respiratory condition created by the coronavirus 2 (SARS-CoV-2) presents a challenge to recognize effective strategies for management and treatment. In general, COVID-19 is an acute disease that can also be fatal, with an ongoing 10.2% case morbidity rate. Extreme illness may bring about death because of enormous alveolar damage and hemorrhage along with progressive respiratory failure. The rapidly expanding information with respect to SARS-CoV-2 research suggests a substantial number of potential drug targets. The most encouraging treatment to date is suggested to be with the help of remdesivir, hydroxychloroquine, and many such repurposed drugs. Remdesivir has a strong in vitro activity for SARS-CoV-2, yet it is not the drug of choice as affirmed by the US Food and Drug Administration and presently is being tried in progressing randomized preliminaries. The COVID-19 pandemic has been the worst worldwide general health emergency of this age and, possibly, since the pandemic influenza outbreak of 1918. The speed and volume of clinical preliminaries propelled to examine potential treatments for COVID-19 feature both the need and capacity to create abundant evidence even in the center of a pandemic. No treatments have been demonstrated as accurate and dependable to date. This review presents a concise precise of the targets and broad treatment strategies for the benefit of researchers. Keywords COVID-19. SARS-CoV-2. Protein targets. Antisense therapy. Repurposed drugs Abbreviations COVID-19 Coronavirus infectious disease 2019 SARS-CoV-2 Severe acute respiratory disorder coronavirus 2 US United States HIV Human immunodeficiency virus 2019-nCoV 2019-coronavirus * Shubhini A.

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Nanotechnology is concerned with the production and use of nano-sized materials. In the development of nanotechnology, the synthesis of metal nanoparticles is a reliable and environmental friendly step. At the present time, the use of the biosynthesis method in the development of metal nanoparticles has been developed as an alternative synthesis route, removing the limitations of traditional synthesis methods such as physical and chemical methods. In the biosynthesis process, researchers are facing challenges to synthesize stable and geometrically controlled Silver Nanoparticles (AgNPs). In the past few years, the plant-mediated synthesis method has proved to be important in the development of stable, low cost and environment-friendly AgNPs and has been described by many researchers. In the past decade, silver nanoparticles (AgNPs) are the most studied and used nanoparticles due to their unique properties. In this review, we have discussed the eco-friendly synthesis route for the development of AgNPs and its application in various fields.