Subjects & Methods: 300 appendectomy specimens were investigated. Biodata of patients on Pathological proforma and specimens was noted. 3-5 µ tissue sections of appendectomy were stained with H & Eosin stain for microscopy. Data was analyzed on SPSS version 22.0 (USA) at 95% CI (P ≤ 0.05). Results: Male to female ratio was 3.61:1 (P=0.0001). Mean (± SD) age was 19.5±5.7 years. Acute appendicitis was noted in 57.66% of specimens. Unusual histopathological findings noted were adenocarcinoma, endometriosis, Crohn`s disease, carcinoid tumors and Enterobius vermicularis. Conclusion: Unusual incidental findings emphasize the importance of histopathological examination of appendectomy specimen for proper diagnosis and timely intervention.
Objectives: Investigating cytopathological characteristics of thyroid swellingsby fine-needle aspiration cytology (FNAC) compared to histopathological examination. StudyDesign: Observational study. Place and Duration: Department of Pathology in collaborationwith Department of Surgery, Liaquat University of Medical and Health Sciences from November2014 to December 2016. Methods: A sample of 100 FNAC specimens was selected as perinclusion and exclusion criteria. FNAC procedure was conducted by technique of “to andfro movements” of needle for thyroid nodules of <1.5 cm size from central part of swelling.Peripheral part was aspirated in cases of large thyroid swellings. Smears were air dried andstained with May–Grunwald Giemsa (MGG) and H & E stain for histopathological examinationby microscopy. Data was analyzed on SPSS 22.0 at 95% confidence interval (p≤0.05). Results:Mean± SD age was noted as 47.6±8.6 years. Of total 200 cases, male and female were 90 (45%)& 110 (55%) respectively. Benign thyroid lesions were noted in 140 (70%), malignant thyroidlesions in 50 (25%) and 10 (5%) proved indeterminate thyroid lesions. FNAC shows sensitivityof 89%, specificity 97% and accuracy of 91%. Conclusion: FNAC is an easy, time escaping,cost- effective, simple procedure and valid technique for the triage of thyroid swellings.
Objectives: Investigating unusual incidental findings in appendectomyspecimens by histopathological examination. Study Design: Observational study. Place &Duration: Department of Pathology, Liaquat University of Medical and Health Sciences fromJanuary 2014 to March 2016. Subjects & Methods: 300 appendectomy specimens wereinvestigated. Biodata of patients on Pathological proforma and specimens was noted. 3- 5 μtissue sections of appendectomy were stained with H & Eosin stain for microscopy. Data wasanalyzed on SPSS version 22.0 (USA) at 95% CI (P ≤ 0.05). Results: Male to female ratiowas 3.61:1 (P=0.0001). Mean (± SD) age was 19.5±5.7 years. Acute appendicitis was notedin 57.66% of specimens. Unusual histopathological findings noted were adenocarcinoma,endometriosis, Crohn`s disease, carcinoid tumors and Enterobius vermicularis. Conclusion:Unusual incidental findings emphasize the importance of histopathological examination ofappendectomy specimen for proper diagnosis and timely intervention.
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