The diverse and magnificent plant kingdom of the world is widely known for its medicinal importance. The potential medicinal properties of plant species have contributed significantly in the development of various herbal therapies for a number of diseases across the globe. The benefits of herbal medicine over allopathic medicine have helped medicinal plants to regain their importance in the field of health and medicine. Cancer is one of the major health problems that have widely affected the world's population. There is a great need to combat this disease with better and more effective medication as compared to existing therapies. A vast number of medicinal plants are known to have biochemical constituents with anticancer properties. The chemical metabolites of natural origin that possess anticancer properties can serve as potential lead compounds in drug designing. This association of medicinal plants and cancer needs further research and experimentation in order to develop and design anticancer drugs. The present review is an effort to compile information on some of the geographically diverse and important medicinal plants that possess anticancer activity.
Centella asiatica commonly known by names like gotu kola, Mandukaparni or Indian pennywort is a small herbaceous perennial medicinal plant belonging to Apiaceae family. Its active metabolites are triterpenoids which includes asiaticoside, asiatic acid, madecassoside, madecassic acid which has wide range of pharmaceutical activities like wound healing, memory enhancer, treatment of skin diseases etc. The present work is aimed to perform phytochemical analysis and estimation of antioxidant activity by DPPH assay. The antioxidant activity by DPPH assay showed maximum IC 50 value in CSC extract than shoot and callus extracts. The quantitative estimation of total phenolic, flavanoids and tannins indicates highest phytochemicals in SC when compared to CC and CSC.
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