Germ cell tumors are composed of a number of histologically different tumor types derived from the primitive germ cells of the embryonic gonad. Teratomas are histological subgroup of germ cell tumors, originating from primordial germ cell. Dermoid cyst or mature teratoma is the most common benign ovarian neoplasm in young and middle aged women. It accounts for approximately 20% and 50% of adult and pediatric ovarian tumors, moreover, malignant transformation occurs in 1-3% of cases. 1,2 Most common being squamous cell carcinoma. Other tumors arising in a mature cystic teratoma include adenocarcinoma, thyroid carcinoma, malignant melanoma, transitional cell carcinoma, sarcoma, carcinoid tumor, and neuroectodermaltumor. 3 The frequency of malignant change increases with increasing age rising to 19% after menopause. However,
Tumors of the orbit are rare diseases in ophthalmic pathology-3.5 to 4%. They include primary and secondary tumors. Their diagnosis pose a great challenge for both clinicians and pathologists since they present with a variety of signs and symptoms and they are often difficult to diagnose at initial stages. To analyse the histomorphological features of orbital tumors and to compare the results of the present study with other studies in the literature. This is a prospective and retrospective study done in Sarojini Devi Eye hospital, Hyderabad at the Department Of Pathology during December 2013 to September 2016. All surgical resected specimens of orbital tumors recieved at the Department of Pathology were included in the study. Variables examined included clinical details, radiological findings and histopathological findings. A Total of 54 cases were studied. Of these, 33 cases were males and 21 cases were females. Age group ranged from 5 years to 62 years. Incidence of the tumors showed bimodal age distribution. The most common tumor was Dermoid cyst. Orbital tumors can occur at various age groups and because of their myriad presentation their diagnosis pose a great challenge. Although imaging studies graphically illustrate the tissue definition, pathological conditions can be assessed definitely only by obtaining tissue specimen surgically.
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