Trichofolliculoma is a pilosebaceous follicle hamartoma in which several hairs are formed within single pilosebaceous unit and protrude out of single orifice. Herein we report a 45-year-old woman with a trichofolliculoma of the eyebrow. Case synopsisA 45-year-old woman presented with an asymptomatic slowly growing swelling over the right eyebrow of 6 months duration. There was no history of similar lesion elsewhere in the past and no similar skin lesion in any family members. The patient could not recall any history of trauma at the site of swelling.Examination revealed a solitary skin colored shiny, firm, non tender nodule of size 0.9X 0.5X 0.5 cm over the infero-medial aspect of the right eyebrow. The nodule had an umbilication in the center with a keratinous plug and a few terminal hairs emerging from it (Figure 1). No other mucocutaneous abnormality was detected and systemic examination was unremarkable. The nodule was excised and sent for histopathological examination. Figure 1. Solitary skin colored shiny, firm, umbilicated nodule with keratinous plug and few terminal hairs emerging over infero-medial aspect of eyebrow.
The elbow is not recognized as common site for cutaneous lupus erythematosus (CLE) lesions. Twelve cases of CLE over the elbows were evaluated for systemic involvement and Cutaneous Lupus Disease Area and Severity Index activity and damage scores and Systemic Lupus Erythematosus Disease Activity Index scoring was done. Histopathological examination of the affected skin was performed in doubtful cases. Most of the patients were women (10, 83.3%) with mean age of 28.75 years. Three patients had only elbow lesions and the remaining nine patients had CLE lesions at sites other than the elbows, of which five had elbow lesions preceding skin lesions elsewhere over the body and three patients were not aware of whether elbow lesions preceded or succeeded CLE lesions at other sites, and one patient had noticed malar rash 9 months prior to elbow lesions. All the patients antinuclear antibody positivity, systemic involvement, and fulfilled criteria for systemic lupus erythematosus. This peculiar localization of CLE to the elbows may be associated with a greater risk of systemic involvement and may be an predictor of flare of LE.
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