The SARS-CoV-2 virus has emerged and rapidly evolved into a current global pandemic. Although bacterial and fungal coinfections have been associated with COVID-19, little is known about parasitic infection. We report a case of a COVID-19 patient who developed disseminated strongyloidiasis following treatment with high-dose corticosteroids and tocilizumab. Screening for Strongyloides infection should be pursued in individuals with COVID-19 who originate from endemic regions before initiating immunosuppressive therapy.
W hole-slide imaging (WSI) technology and machine learning (ML)-aided diagnostics are primed to bring us new ways of seeing, learning, and understanding human pathology. 1 Physicians, investors, and the public are being promised that these technologies will provide ''faster, more accurate diagnosis of disease'' 2 and allow pathologists to ''make better decisions for their patients.'' 3 We worry, however, that these technological advances also come with practical and ethical risks. One particular concern is that WSI and ML are being accompanied by a monopolization of slides, technology, and intellectual property. Some digital monopolies in this arena are de facto whereas others are legal, but both may lead to a loss of shared access to current and future knowledge. We see 3 long-term risks to the monopolizing forces developing in anatomic pathology: the privatization of seeing, the privatization of experience, and the privatization of understanding. To counter these trends, we recommend that our profession create a digital pathology commons.
Perianal keratoacanthomas are rare, with 10 cases reported to date. Perineal keratoacanthoma has not previously been described. In this report, we describe two cases of keratoacanthoma, one perianal and one perineal. Both lesions show prominent dyskeratotic keratinocytes, with striking and curious histologic resemblance to subungual keratoacanthoma.
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