Complex abdominal wall defects might be challenging for human and veterinary surgeons worldwide. Defects from trauma or congenital causes may lead to hernias development. The introduction of meshes to reinforce hernia repairs has improved surgical outcomes and several synthetic and biologic materials have been used. In this context, biomaterial prosthesis seems to be a satisfactory solution when managing great abdominal wall defects. The aim of the current study is to evaluate the bovine tunica albuginea (BTA) preserved in honey as graft material for rats' abdominal wall reinforcement in incisional herniorrhaphy surgery as well as its viability, cicatrization and integration into the host tissue. Wistar rats were assigned to two main groups: 1) animals (n = 20) underwent median longitudinal laparotomy followed by laparorraphy with suture of the bovine tunica albuginea (BTA) graft as abdominal wall reinforcement; and 2) animals (n = 20) underwent only laparotomy and subsequent laparorrhaphy. Rats were clinically evaluated until euthanasia at post-surgical day 7, 14, 21 and 28. Necropsy and histopathological analysis of abdominal wall fragments were performed to compare groups and subgroups findings. BTA promoted abundant fibrosis, providing resistance and low postoperative complication rates. Besides, animals did not show rejection signs to the implant. In conclusion, BTA preserved in honey is an affordable, easy collection and handling biomaterial for graft, demanding simple surgical implantation technique for abdominal wall repair in rats.
23. Zhao Y., et al. "Time-dependent bladder tissue regeneration using bilayer bladder acellular matrix graft-silk fibroin scaffolds in a rat bladder augmentation model". Acta Biomaterialia 23 (2015): 91-102. 24. Kosan M., et al. "Tissue reactions of suture materials (polyglactine 910, chromed catgut and polydioxanone) on rat bladder wall and their role in bladder stone formation". Urological Re-
RESUMOO objetivo do trabalho é relatar a ocorrência de megaesôfago secundário associado à persistência do quarto arco aórtico direito em dois cães das raças pastor alemão e pastor canadense, cujo manejo clínico tardio não apresentou resultados satisfatórios, mostrando a necessidade da correção cirúrgica precoce. As anomalias dos anéis vasculares são malformações congênitas dos principais vasos da base do coração que podem ocasionar o envolvimento e constrição parcial ou completa do esôfago ou da traqueia. Entre essas anomalias, a persistência do quarto arco aórtico direito, a mais frequente em cães, pode resultar em alterações digestivas, como o megaesôfago. Neste trabalho, são descritos dois casos de megaesôfago secundário à persistência de arco aórtico direito em cães com dois meses de idade, atendidos no Hospital Universitário de Medicina Veterinária da Universidade Federal Fluminense (HUVET-UFF). A sintomatologia clínica aliada ao esofagograma contrastado permitiu o diagnóstico de anomalia do anel vascular e, por conseguinte, do megaesôfago. Em ambos os casos foi identificada pneumonia por aspiração do conteúdo regurgitado. O procedimento cirúrgico é a única possibilidade de sobrevida para pacientes acometidos por essa enfermidade e deve ser instituído o mais precocemente possível, uma vez que o tratamento conservador não é suficiente para a recuperação do paciente e a garantia da qualidade de vida. PALAVRAS-CHAVE: anomalia de anel vascular, canino, regurgitação.
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