The study comprised 180 anaemic cats. Descriptive and survival data were obtained. Cats were classified by aetiology of anaemia development and degenerative, anomalous, metabolic, miscellaneous, neoplastic, infectious, inflammatory, immune-mediated, toxic, traumatic or vascular disease (DAMNITV) classification and anaemia severity. Sixty-four (35.6%) cats had mild [packed cell volume (PCV)/haematocrit (HCT) 20-24.9%], 58 (32.2%) moderate (14-19.9%), 23 (12.8%) severe (11-13.9%) and 35 (19.4%) very severe (<10.9%) anaemia. By aetiology of anaemia development, bone marrow (BM) abnormalities were more common (95, 52.8%) than haemorrhage (37, 20.6%) or haemolysis (19, 10.6%). By DAMNITV classification, infectious diseases were more common (39, 21.7%) than neoplasia (36, 20%), metabolic (21, 11.7%), trauma (15, 8.3%), miscellaneous (14, 7.8%), inflammatory (11, 6.1%), immune-mediated (11, 6.1%), anomalous (8, 4.4%), toxic (2, 1.1%) or vascular disease (1, 0.6%). BM abnormalities were significantly associated with more severe anaemia (P = 0.003). Most cats (112, 62.2%) survived to discharge whereas 55 (30.6%) were euthanased and 13 (7.2%) died. Survival to discharge was not associated with anaemia severity but was associated significantly with aetiology of anaemia development (P = 0.046), as cats with haemolysis were more likely to survive to discharge than cats with BM abnormalities. Survival to discharge was also associated significantly with DAMNITV classification (P = 0.010), with cats with neoplasia being less likely, and cats with immune-mediated disease more likely, to survive to discharge. Cox regression analysis found that survival was not associated with anaemia severity, but was associated with DAMNITV classification (P = 0.011) and age (P = 0.082), with cats with immune-mediated disease and younger cats more likely to survive.
This article describes the MRI features of a middle ear cholesteatoma in an 8 yr old flat-coated retriever. Physical examination revealed pain on opening the jaw, and otoscopic examination showed tympanic membrane rupture associated with hyperplastic tissue at the entrance of the middle ear. Standard MRI sequences allowed for the identification of a severely expanded bulla containing material that was isointense to brain tissue on T1-weighted images and of mixed intensity on T2-weighted and fluid-attenuated inversion recovery sequences. No postcontrast enhancement of the content was present, but the lining of the bulla was partially enhanced. The images allowed evaluation of the surgical margins and the secondary changes due to the expansion of the mass. Surgery was performed and histopathology confirmed the presumptive diagnosis of cholesteatoma. In the present case, MRI appeared to serve as a good alternative to computed tomography for the diagnosis of cholesteatoma.
Parasites were extracted from the stomach and small intestine of 118 horses at slaughter. The most abundant species was the tapeworm Anoplocephala perfoliata. Maximum likelihood analysis was used to investigate the relationship between the number of worms and their total weight, and the ability of an antibody-based elisa to diagnose the level of infection. The total weight of tapeworms increased towards a maximum as the number of worms increased, suggesting a population density-dependent constraint on the weight. The number of A perfoliata present could be predicted approximately from the results of the elisa. Although wide variation in elisa optical densities confound interpretation in individual animals, tests on groups of animals could provide a useful reflection of overall levels of infection.
Objectives To assess the performance of three bench‐top chemistry instruments for the analysis of canine effusions. Acceptable results were compared with those obtained by a reference chemistry analyser. Methods Total protein, albumin, creatinine and bilirubin concentrations were measured in 74 effusions using the VetScanVS2, VetTest8008 and SpotchemEZ analysers. Cholesterol and triglyceride concentrations were also measured by the VetTest and Spotchem. Results were analysed using Westgard's error analysis, Spearman's correlation, Bland‐Altman plots and Deming regression. Results were considered acceptable when observed total error (TEobs) was less than allowable total error (TEA). Results VetScan error analysis revealed acceptable results for total protein (TEobs=1·11, TEA=4·7) and creatinine (TEobs=42·2, TEA=78·1). Correlation was fair for protein (rs=0·66) and creatinine (rs=0·76), but poor and not significant for bilirubin (rs=0·01, P=0·08), precluding error analysis. VetTest error analysis was acceptable for creatinine only (TEobs=5·55, TEA=25·5). Correlation was good (rs=0·81). The difference plot revealed a bias (95% confidence interval) of −1·5 (−37 to 40) and four outliers. The Spotchem did not generate a precise arithmetic value in most (56·9 to 73·6%) samples, precluding further analysis. Clinical Significance Acceptable results were obtained for total protein (VetScan) and creatinine [Vetscan, Vettest (with good correlation)]. The Spotchem is of limited value in canine effusion analysis.
Ehrlichia canis infection can cause a serious tick-borne disease in dogs. Here we report clinical details and outcomes of E. canis cases in UK dogs.
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