Highlights Multicentric prospective observational study of 94 EEG in 62 patients with COVID-19. The most frequent EEG finding was generalized slow-wave activity (66 %). Epileptiform activity (19 %) included NCSE, seizures and interictal discharges. Mortality was increased in patients with cancer comorbidity. Mortality was increased in patients who required an EEG during the 3 rd week.

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Maintenance of cell morphology is essential for normal cell function. For eukaryotic cells, a growing body of recent evidence highlights a close interdependence between mitochondrial function, the cytoskeleton, and cell cycle control mechanisms; however, the molecular details of this interconnection are still not completely understood. We have identified a novel protein, Bot1p, in the fission yeast Schizosaccharomyces pombe. Mitochondria are energy-generating organelles that participate in multiple cell signaling cascades, which allow continuous communication with the rest of the cell. Recent studies underline the close relationship between mitochondria and cell morphology control, indicating that while mitochondrial movement, morphology, and function are regulated by the cytoskeleton in mostly uncharacterized ways, mitochondrial function is essential for both maintenance of normal morphology, particularly in neuronal cells, and for normal cell cycle progression (1, 29).The fission yeast Schizosaccharomyces pombe has been extensively used as a powerful genetic model organism for studying the molecular mechanisms of morphology and cell cycle control.

Biomass-derived isosorbide (IS) was converted into a mono-glycal (i.e. vinyl ether) derivative (Gly-IS) to investigate its efficacy for cationic polymerization.

Patient experience is an important factor across diverse healthcare delivery settings. Despite enhanced attention to and advances in patient experience, many of the published initiatives focus on in-hospital care and opportunities have been identified to continue to strategically address patient experience in the ambulatory setting. This quality improvement initiative presents the development of an interprofessional approach to patient experience in a freestanding ambulatory oncology center. The objective of this initiative was to improve and sustain patient experience, as reflected in the Consumer Assessment of Healthcare Providers and Systems (CAHPS) scores via Press Ganey. This approach consisted of redesigning a previously nurse-led patient experience team to include interprofessional providers, including physicians, physical therapists, and administrators. Interventions including specialized training in CAHPS  reports and scoring for both committee members and center staff, quarterly reporting of data to interprofessional teams by service line, and standardization of the communication of best practices to improve patient experience across the center. In addition to outlining the components of the interprofessional initiative, which may be readily translated across diverse care settings, this article demonstrates improved and sustained patient satisfaction data, as measured by 2 years of Consumer Assessment of Healthcare Providers and Systems (CAHPS ) scores. Findings from this best practice suggest that an interprofessional approach with defined interventions can improve patient experience in the ambulatory setting, resulting in sustained, measurable improvement.

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Soil health is a complex phenomenon that reflects the ability of soil to support both plant growth and other ecosystem functions. To our knowledge, research on extracellular electron transfer processes in soil environments is limited and could provide novel knowledge and new ways of monitoring soil health. Electrochemical activities in the soil can be studied by inserting inert electrodes. Once the electrode is polarized to a favorable potential, nearby microorganisms attach to the electrodes and grow as biofilms. Biofilms are a major part of the soil and play critical roles in microbial activity and community dynamics. Our work aims to investigate the electrochemical behavior of healthy and unhealthy soils using chronoamperometry and cyclic voltammetry. We developed a bioelectrochemical soil reactor for electrochemical measurements using healthy and unhealthy soils taken from the Cook Agronomy Farm Long-Term Agroecological Research site; the soils showed similar physical and chemical characteristics, but there was higher plant growth where the healthy soil was taken. Using carbon cloth electrodes installed in these soil reactors, we explored the electrochemical signals in these two soils. First, we measured redox variations by depth and found that reducing conditions were prevalent in healthy soils. Current measurements showed distinct differences between healthy and unhealthy soils. Scanning electron microscopy images showed the presence of microbes attached to the electrode for healthy soil but not for unhealthy soil. Glucose addition stimulated current in both soil types and caused differences in cyclic voltammograms between the two soil types to converge. Our work demonstrates that we can use current as a proxy for microbial metabolic activity to distinguish healthy and unhealthy soil.