HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.
This publication is to announce the database of the Moss Flora of Russia at http://arctoa.ru/Flora/ basa.php. It also explains the strategy and approaches so as to be maximally useful for the publication of the Moss Flora of Russia, a six-volume print edition that was started in 2017. The database currently contains over 128 000 records; it is shown to be reasonably complete for illustrating the species distribution within the expanded territory of the country. A number of scripts allow instant comparison of various territories, highlighting hotspots and underexplored areas. Problems of data control and presentation are discussed. Резюме В данной статье анонсируется база данных по флоре мхов России, размещенная по адресу http://arctoa.ru/Flora/basa.php. В ней также представлены стратегия и подходы к максимально полному ее использованию для подготовки публикации шеститомного печатного издания "Флора мхов России", которое стартовало в 2017 г. В настоящее время в базе представлено более 128 000 образцов; показано, что уже сейчас распространение видов на территории страны отражается адекватно. Наличие нескольких скриптов позволяет быстро проводить сравнение флор разных территорий, которое выявляет наиболее флористически богатые регионы и "белые пятна" в исследовании флор. Обсуждаются проблемы контроля за внесением информации и ее представ-лением.
Multipotent mesenchymal stromal cells (MSCs) participate in the formation of bone marrow niches for hematopoietic stem cells. Donor MSCs can serve as a source of recovery for niches in patients with graft failure (GF) after allogeneic bone marrow (BM) transplantation. Since only few MSCs reach the BM after intravenous injection, MSCs were implanted into the iliac spine. For 8 patients with GF after allo-BMT, another hematopoietic stem cell transplantation with simultaneous implantation of MSCs from their respective donors into cancellous bone was performed. BM was aspirated from the iliac crest of these patients at 1-2, 4-5, and 9 months after the intraosseous injection of donor MSCs. Patients' MSCs were cultivated, and chimerism was determined. In 6 out of 8 patients, donor hematopoiesis was restored. Donor cells (9.4 ± 3.3%) were detected among MSCs. Thus, implanted MSCs remain localized at the site of administration and do not lose the ability to proliferate. These results suggest that MSCs could participate in the restoration of niches for donor hematopoietic cells or have an immunomodulatory effect, preventing repeated rejection of the graft. Perhaps, intraosseous implantation of MSCs contributes to the success of the second transplantation of hematopoietic stem cells and patient survival.
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