Introdução: Dentre as infeções sexualmente transmissíveis a sífilis se destaca como grande problema de saúde pública. Apesar de ser uma doença de fácil manejo e evitável, se torna preponderante discutir a importância do tratamento das gestantes soropositivas, uma vez que há grandes sequelas, não só para a criança, como também reflexos nos coeficientes de saúde. Objetivos: Ratificar a importância do tratamento das gestantes com sífilis por meio da análise de dados epidemiológicos do SINAN. Métodos: Trata-se de um estudo ecológico compreendendo informações das unidades federativas do Brasil, a partir da observação, entre 2014-2019, da incidência e prevalência da sífilis em gestantes e da sífilis congênita e os coeficientes que rodeiam essa temática. Discussão: A sífilis durante a gestação ainda ocorre em proporções significativas nas mulheres, ratificada pelos 18,1% (24.130) dos conceptos menores de um ano de idade acometidos pela doença em 2019. Embora em 2019 o número de casos de gestantes com sífilis tenha se reduzido, percebe-se falha no esquema de tratamento sendo que apenas 2,3% (1.462) delas foram tratadas adequadamente. Apesar de 61.127 mulheres terem sido testadas para sífilis em 2019, apenas 32,9% (20.163) realizaram o pré-natal, o que evidencia falha na captação das gestantes para realização do mesmo. Conclusão: Fica evidente que tratar essas mulheres garante não só qualidade de vida para as gestantes bem como para as crianças, além de gerar melhores coeficientes que indicam melhor profilaxia, captação efetiva nas fases precoce, informação e efetivação das políticas públicas de saúde.

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Introduction: Migraine infarction is one of the rare complications of migraine with aura, characterized by the persistence of aura symptoms for more than sixty minutes, associated with ischemic brain damage in the appropriate territory, demonstrated by neuroimaging examination. In spite of several cases reported in the literature correlate cerebral infarction with migraine, it is still unclear which magnetic resonance (MRI) pattern is associated with this condition. Cortical laminar necrosis (CLN) is a type of cortical infarction characterized by selective and late necrosis, especially in the third layer of the cerebral cortex, a region where there is greater vulnerability to metabolic stress. On MRI, CLN is characterized by an increase in cortical signal intensity on T1-weighted images with a typical curvaceous gyriform distribution. The goal of this study was to demonstrate, throughout a literature review, a possible association between migraine with aura, migraine infarction and cortical laminar necrosis without neuroimaging examination.Methods: A systematic research was performed in databases at the PubMed and Embase in February 2021. The search terms used for 'Migraine' or 'Migraine with aura' or 'Migrainous Infarction' combined with 'Cortical Laminar Necrosis', using their respective variations of the according as MeSH and Emtree. It was articles published in English, in pair reviewed journals, during any period and submitted to studies relevant to clinical questions, which revealed cases of Laminar Cortical Necrosis associated with migraine, were included. Studies that do not attempt the criteria, was excluded.Results and Discussion: The search for selected databases resulted in 24 articles. Excluding 14 articles were not chosen because they are not CLN, and 1 article published in conference abstracts that we did not choose for this review. Finally, 8 original studies were selected and critically analyzed in this review. There was a prevalence in hundred percent of the cases analyzed with migraine with aura (Table 1), and all of them manifested additional neurological symptoms. In two cases, the etiology was of familiar legacy of genetic origin, which consisted of a familial hemiplegic migraine. MR was performed days after the begining of symptoms, ranging from the 3rd to the 30th day. In all cases, was observed unilateral cortical hypersignal on axial T1-evaluation. Unilateral T1-evaluation cortical hyperintensity with Gadoliun and FLAIR was also identified in most of the cases. Less commonly, alterations to the DWI and ADC sequences are seen. Conclusion: Despite being a rare manifestation, this review demonstrates that CLN can be recognized as an attribute associated with migraine with aura, spread the spectrum of neuroimaging acts correlated with migraine. Our goal was narrow the boundaries between neurovascular disease on imaging and a migraine with aura, helping neurologists to recognize this association. Before this scene of high predominance of migraines, further studies are needed to elucidate its relationship with CLN, as its pathophysiology and group of patients with risk factors, who may benefit from prophylactic treatment.