IntroductionIdiopathic dilated cardiomyopathy causes great impact but many aspects of its
pathophysiology remain unknown.ObjectiveTo evaluate anatomical and histological aspects of hearts with idiopathic dilated
cardiomyopathy and compare them to a control group, evaluating the behavior of the
perimeters of the atrioventricular rings and ventricles and to compare the
percentage of collagen and elastic fibers of the atrioventricular rings.MethodsThirteen hearts with cardiomyopathy and 13 normal hearts were analysed. They were
dissected keeping the ventricular mass and atrioventricular rings, with lamination
of segments 20%, 50% and 80% of the distance between the atrioventricular groove
and the ventricular apex. The sections were subjected to photo scanning, with
measurement of perimeters. The atrioventricular rings were dissected and measured
digitally to evaluate their perimeters, later being sent to the pathology
laboratory, and stained by hematoxylin-eosin, picrosirius and oxidized resorcin
fuccin.ResultsRegarding to ventricles, dilation occurs in all segments in the pathological
group, and the right atrioventricular ring measurement was higher in idiopathic
dilated cardiomyopathy group, with no difference in the left side. With respect to
collagen, both sides had lower percentage of fibers in the pathological group.
With respect to the elastic fibers, there was no difference between the
groups.ConclusionThere is a change in ventricular geometry in cardiomyopathy group. The left
atrioventricular ring does not dilate, in spite of the fact that in both
ventricles there is lowering of collagen.
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