1. Small cell neuroendocrine carcinoma of the larynx is a rare entity. The prognosis of this type of tumor is very poor, and the clinical course is rapidly fatal. We report a case of a 62-year-old patient who presented with a two years history of chronic dysphonia. Laryngoscopy revealed a bulging lesion in the glottic and supraglottic region. Morphological and immunohistochemical studies revealed a small cell neuroendocrine tumor. This patient received chemotherapy associated with concomitant radiotherapy with a good clinical and radiological evolution.
Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor that is locally aggressive and has a high rate of recurrence after surgical intervention. We repot a case of a 73-year-old man presented an abdominal mass evolving over 30 years. Physical examination revealed a multinodular lesion of 12x10 cm, slightly fixed to the deep tissues. A skin biopsy was performed. Histopathological examination rconfirmed the diagnosis of dermatofibrosarcoma protuberans. CT imaging was suggestive of a subcutaneous supra-fascial mass of 67x89x98 mm, infiltrating the left rectus abdominis muscle. The patient underwent surgical resection of the tumor and the muscle’s fascia. The lateral margins were between 5 to 13 cm. The deep resection margin was at 0,1 cm. The mainstay of treatment for DFSP is complete surgical excision with histologically negative margins. Radiation should be considered as an adjuvant to resection if margins are positive.
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