Objective COVID-19 has recently emerged as a serious threat to global health. This study examined the laboratory investigations of patients with COVID-19, with an emphasis on liver enzymes. Methods This retrospective, single-center study was performed on patients with COVID-19 who were admitted to Imam Reza Hospital, Iran from March 2020 to February 2021. Laboratory tests included a complete blood cell count, white blood cell (WBC) count, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio, and levels of aspartate aminotransferase, alanine aminotransferase (ALT), and alkaline phosphatase. Patient survival was among the outcome measures investigated in association with laboratory findings. Results We enrolled 77 patients with COVID-19 and 63 healthy controls. In comparison with the control group, patients with COVID-19 showed COVID-19 increased ALT, WBC, neutrophils, NLR, and PLR, and decreased platelet counts and lymphocytes. Conclusion Although elevated levels of AST, NLR, PLR, and LMR were found in patients with COVID-19, they were not linked to mortality. Given the presence of AST in other tissues, the influence of SARS-CoV-2 on the liver should be interpreted with caution.

Objective Thyroid cancer is the most common cancer of the endocrine and is apparent in about 5 percent of thyroid nodules. Platelets have been shown to play an important role in chronic inflammation, cancer progression, and metastases. Recent research has been done on the correlation between platelet factor and many other types of cancer. This study aimed to investigate the diagnostic accuracy of platelet factor and other CBC parameters in papillary thyroid carcinoma. Material and Methods Thirty hundred and fifty patients were divided into two groups retrospectively. Group 1: papillary thyroid carcinoma patients (n = 150). Group 2: normal healthy subjects (n = 200). PLT, MPV, PDW, and CBC parameters were compared between groups, and p < 0.05 was accepted as significant Results The neutrophil count and NLR (neutrophil to lymphocyte ratio) were significantly higher, while the Hb, PLT, MPV, RDW, lymphocyte, and monocyte count, were significantly lower in patients compared with the control group. These parameters scored low in all parameters of diagnostic accuracy, with overall accuracy ranging between 41 and 66%. Conclusions NLR, MPV, and PLT are relatively inexpensive and widely available from routine blood tests. Although we found higher NLR values and lower PLT and MPV values in patients with papillary thyroid carcinoma, these factors cannot effectively diagnose thyroid cancer.

Meconium-stained amniotic fluid (MSAF) affects 15-20% of term pregnancies. Recent studies have shown that MSAF has adverse effects on neonatal outcomes. There is no scientific consensus on the incidence of fetal distress in MSAF neonates, and most cesarean sections due to MSAF are unnecessary. The present study was conducted to assess umbilical artery blood pH in neonates with MSAF and to examine whether there is a relationship between MSAF and fetal distress. A clinical survey case-control was conducted on the neonates of 200 pregnant women admitted to a delivery unit of the obstetrics and Gynecology center in Amir al-Momenin Hospital, Zabol in 2014. Neonates born with MSAF made up the case group, and the control group consisted of neonates born with clear amniotic fluid. Umbilical cord arterial pH, gestational age, gender, mode of delivery, and one and five-minute Apgar scores were considered in both groups. The mean pH of the umbilical cord artery blood in the infants of the case group was 7.25, and the mean pH of the umbilical cord artery in the infants of the control group was 7.29 (P = 0.93). The mean gestational age in the case and control groups was 40.08 weeks and 38.32 weeks, respectively (P= 0.03). In this study, a cesarean delivery (P=0.001) and female gender (P= 0.016) were higher in the case group than in the control group. MSAF does not necessarily imply fetal distress, so urgent cesarean sections are unnecessary. This study showed that based on the acidity variables of the umbilical cord artery, there is no statistically significant correlation between the Apgar score at the 1st and 5th minute. While a significant difference has been observed between the type of delivery, gestational age and baby's gender.

Background. Mental disorders during pregnancy can be associated with adverse delivery and neonatal outcomes, as well as a higher risk of postpartum mental disorders. Objectives. This study was conducted to determine the factors associated with mental disorders in pregnant women. Material and methods. Using stratified multistage random sampling, 332 participants were selected among pregnant women covered by health centres for prenatal care from April to September 2019 in the west of Iran. After obtaining informed consent from these people, the demographic questionnaire and the Persian version of the Goldberg GHQ-28 questionnaire were completed for them by a trained midwife. The data was analysed in SPSS 22 using descriptive statistics, the t-Test and ANOVA. Results. The mean age and mean gestational age of the 332 pregnant women under study were 29.01 ± 5.44 years and 22.95 ± 8.95 weeks, respectively. About 32.5% (n = 108) of the women were suspected of having general mental health disorders. The mean scores of the subscales and general mental health disorders were significantly higher in pregnant women with unwanted pregnancy, marital dissatisfaction, a history of domestic violence and in those between 43-47 years of age (p < 0.05). However, the differences between the mean scores of the disorders were not statistically significant in women with a history of abortion and infertility, gestational age and gender, educational levels and occupation. Conclusions. The results of this study showed that 32.5% of the pregnant women were suspected of having general mental health disorders. Mental health disorders were more common in pregnant women with unwanted pregnancy, marital dissatisfaction, a history of domestic violence in those between 43-47 years of age.