Six patients with medically intractable partial epilepsy (IPE) underwent seizure localization with intracranial EEG using intracerebral or subdural electrodes. No surgical resection was performed, but all had seizure remission ranging from 11 months to 15 years. Invasive monitoring may rarely produce remission of IPE, possibly through interruption of seizure propagation pathways.

We report on a 56-year-old woman with Parkinson disease who had previously been implanted with bilateral deep brain stimulation (DBS). She was hospitalized after a 2-year course of severe depression with psychotic features and physical as well as mental decline. She underwent 2 rounds of successful electroconvulsive therapy (ECT), improving both her physical and mental health without any adverse effects to the patient or the DBS. This is a fourth reported case of ECT being successfully and safely administered in a patient implanted with DBS. This is the first case report of bitemporal ECT in a patient with bilateral DBS. It is also the first case report using the MECTA device and the first case report of a successful and safe second course of ECT after relapse of this patient's depression.