A new and promising methodology for the synthesis of the tetramic acid family of antibiotics was developed. The first synthesis of N‐2,4‐dimethoxybenzyl tirandalydigin (1), as well as a synthesis of streptolic acid (2), was achieved in a highly stereoselective manner.
Für die Synthese von Antibiotika der Tetramsäure‐Familie wurde eine vielversprechende Methode entwickelt. Die erste Synthese von N‐(2,4‐Dimethoxybenzyl)tirandalydigin (1) und eine Synthese von Streptolsäure (2) ergaben hohe Stereoselektivitäten.
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