Psychological distress in 248 evacuees from a volcanic eruption was evaluated using a 30-item General Health Questionnaire (GHQ-30) at four time points after evacuation: 6 months, 12 months, 24 months and 44 months. The proportion of evacuees with psychological distress (defined as a GHQ score ≥ 8) significantly decreased from 66.1% (6 months) to 45.6% (44 months). The GHQ mean score significantly improved from 12.6 to 8.9. Investigation of each factor on the GHQ showed progressive improvement over time in 'anxiety, tension and insomnia' and 'anergia and social dysfunction'. However, 'depression' began to improve only after 44 months and 'interpersonal dysfunction' started to worsen after 12 months. The dysfunction in interpersonal relationships continued at 44 months. Examination of the relation between GHQ mean scores and age group showed that recovery from psychological distress was more difficult in middle-aged and older evacuees than in younger evacuees.

We conducted Goldberg's 30-item General Health Questionnaire (GHQ) on 1,216 Japanese general population aged 40-92. Among them, 9.8% of males and 13.7% of females scored over the cut-off point which is used to indicate minor psychiatric disorders. Factor analysis was carried out using the Likert method and eight factors labelled as follows were selected: depression, anxiety and tension, anergia, interpersonal dysfunction, difficulty in coping, insomnia, anhedonia and social avoidance. The mean value of the standardized scores for each age-sex group indicated that changes in sex-age social roles with age affect the mental health of the general population.

ABSTRACT. A 7-year-old, male, mixed breed dog was referred to the Veterinary Teaching Hospital at Kitasato University because of anorexia, lameness and multiple cutaneous lesions. Observation of bone marrow plasmacytosis, osteolytic bone lesions, serum myeloma protein and cutaneous infiltration of myeloma cells led us to a diagnosis of multiple myeloma (MM) with cutaneous involvement. Polymerase chain reaction and sequence analysis for the rearranged genes of immunoglobulin and T-cell receptor demonstrated that the neoplastic cells found in skin lesions or bone marrow are of B-lymphocyte lineage and share a common original precursor cell. The dog was treated with UW-Madison protocol or melphalan/prednisone protocol and survived 175 days. This is rare case of anaplastic MM with cutaneous involvement in dog.

Abstract. Molecular screening of GM1 gangliosidosis in Shiba dogs was carried out in northern Japan using blood smear specimens after prolonged storage. Of 125 specimens obtained from 3 veterinary teaching hospitals for this screening, 68 specimens (54%) were adequate for direct amplification in a polymerase chain reaction (PCR)-based DNA test, and the percentage of adequacy was different at each hospital (34%, 73%, and 100%), suggesting that the amount of blood on the smear and the storage condition of specimens may affect adequacy. Of the 68 dogs examined, 2 dogs (2.9%) were heterozygous carriers for this disease and the other dogs were all genotypically normal. The results suggest blood smear specimens can be useful for PCR testing after prolonged storage provided specimens contain a generous amount of blood and have been adequately stored. The study also suggests that GM1 gangliosidosis may be widely prevalent in the Shiba dog population in northern Japan.

One-quarter of the residents (about 52 000) in the disaster area around the volcanic eruption area of Mt UnzenFugen have been forced to evacuate over a 3 year period.We conducted a psychological controlled study using the GHQ-30 for evacuees.As a result, the percentage of people with a high score over 8 points was 67% of evacuees, markedly higher than 10% of the control group. Sonie niental support activities, such as counseling by conimunity nurses and crisis intervention/niedication by psychiatrists and others, have been pronioted. Subjects who received a psychiatric intervention had good outcome as a whole.The nature of psychiatric problenis among disaster evacuees and the necessity of long-term support are discussed in this paper.