Incisional random skin biopsy, not punch biopsy, is an appropriate method for diagnosis of intravascular large B-cell lymphoma: A clinicopathological study of 25 patients [published online ahead of print 4 January 2019]. Br J Dermatol.

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early-stage MF does not necessarily imply disease progression, but merely represents an activated T-cell phenotype. Lack of cytotoxic markers would support a memory T-cell origin as well. Further investigations about the pathomechanism of these phenomena are needed. The patient in this manuscript has given written informed consent to publication of his case details.

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sun-exposed areas. As the present case showed a positive photopatch test at a low dose and skin eruptions starting at 2 weeks after first administration, we concluded that the case had a photoallergic reaction.Although there have been two English-language reports of prochlorperazine possibly being associated with photosensitivity, those reports did not describe photopatch tests. 2,3 Therefore, our case is the first of prochlorperazine-induced photosensitivity to be confirmed by a photopatch test in English.Unfortunately, our device was temporarily unable to generate UV-B radiation. Moreover, prochlorperazine has been reported to cause drug-induced photosensitivity to UV-A. 2 The absorption wavelength of prochlorperazine is 254 nm. 4 Hence, we performed only a UV-A test. Regarding the reagent concentration for the photopatch test, we chose a lower concentration than usual with reference to a case report in Japanese. 5Although a number of photosensitivity cases related to phenothiazine have been reported, prochlorperazine-induced photosensitivity is quite rare. The reason for the difference in those frequencies remains to be clarified.We should be aware of photosensitivity when skin eruptions occur during administration of prochlorperazine.