We have found a simple and novel synthetic method for obtaining a chiral polymer from an achiral monomer by using a chiral catalytic system. The chirality of the polymer was caused only by a one-handed helical backbone, and the polymer had no other chiral structures in the side groups. In addition, the helical conformation was stable in solution by itself. This is the first example of helix-sense-selective polymerization of a substituted acetylene. The stability of the helicity was found to be caused by intramolecular hydrogen bonds.
Elecanacin, a Novel New Naphthoquinone from the Bulb of Eleutherine americana.-Elecanacin (I) and isoeleutherol (II) are isolated and their structures are elucidated by spectroscopic methods. Compound (II) exhibit inhibitory activity against HIV. -(HARA, H.; MARUYAMA, N.; YAMASHITA, S.; HAYASHI, Y.; LEE, K.-H.; BASTOW, K. F.; CHAIRUL,; MARUMOTO, R.; IMAKURA, Y.; Chem.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.