Background: Abnormal uterine bleeding is the Common pre senting complaint in Gynaecology Outpatient Department in all age groups. It is due to the anovulatory cycles which are commonly seen in adolescent and perimenopausal women. Abnormal uterine bleeding is caused by wide variety of organic or nonorganic causes. Histopathological examination of endometrial sample remains the gold standard for diagnosis of endometrial pathology.
Non-specific granulomatous prostatitis is the most common type of granulomatous prostatitis. There is no specific pattern of clinical, biochemical and ultrasound findings that allows the diagnosis of granulomatous prostatitis or differentiates it from prostatic carcinoma. Hence, histomorphological diagnosis is the gold standard in differentiating various prostatic lesions.
and included 331 cases of lymph node biopsies. Detailed clinical history like age, sex, site, presenting complaints and clinical diagnosis was noted. Relevant findings and investigations were recorded. The study was approved by institutional ethical committee.Eligibility criteria adopted in our study: 1) Inclusion criteria: all type of lymph node specimens and all age groups.2) Exclusion criteria: inadequate samples and poorly preserved tissue were excluded.All cases of lymph node biopsies were received in 10% formalin. The gross morphological features like size of node, shape, color, consistency, presence of necrosis and matting were noted and taken sections from each. The specimens were processed in automated tissue processor and 4-5 micron thick paraffin embedded sections were taken and stained by Haematoxylin and
ABSTRACTBackground: Lymph node is affected by various types of lesions, both non-neoplastic (inflammatory) or neoplastic. Due to non-specific symptoms, the clinical diagnosis are usually delayed thus lymph node biopsy is mandatory to arrive at specific diagnosis for appropriate management.Objective: 1) To study the spectrum of lymph node pathology with clinical correlation. 2) To study the different histological patterns of lymph node lesions and classify them into major categories.
Methods:The present study was a prospective observational type of study and included 331 patients who presented with lymph node enlargement in a tertiary care hospital over a period of 3 years from Jan 2013 to Dec 2015. Detailed clinical history was noted. The specimens were routinely processed and stained by Haematoxylin and eosin. Special stains along with immunohistochemistry were done whenever required.Result: A total of 331 lymph node biopsies were studied. Age distribution varied from 4 to 81 years with male to female ratio of 1:1.4. Non -neoplastic lesions comprised of maximum cases (80.06%) while neoplastic lesion were present in (19.93%) cases. Reactive lymphadenitis was the predominant non-neoplastic finding followed by granulomatous lymphadenitis. Neoplastic lesions were included 3.61% cases of lymphoma and 16.31% cases of metastatic lesions.
Conclusion:Lymphadenopathy is not uncommon in our region so lymph node biopsy is an important tool for early diagnostic and prognostic purpose. Reactive lymphadenitis was the most common cause of lymphadenopathy followed by granulomatous lymphadenitis.
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Malignant Peripheral Nerve Sheath Tumours (MPNST) are rare spindle-cell sarcomas which are derived from the schwann cells or the pleuripotent cells of the neural crest. MPNSTs are usually located in the peripheral nerve trunk roots, extremities and in the head and neck region. These tumours may arise
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