Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated variants are not correlated with protein-coding changes, suggesting that polymorphisms in regulatory regions probably contribute to many disease phenotypes. Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues

No abstract

No abstract

The LibQUAL+TM survey was conducted to determine user satisfaction and expectations concerning library service quality. The results of the "22 items and a box" constituted a rich source of information for the University of Idaho (UI) Library's strategic planning process. Focusing on graduate students, this study used three methodologies to analyze survey results. The first method, internal benchmarking, compared UI graduate students to UI faculty, staff, and undergraduates. Secondly, external benchmarking using score norms evaluated UI graduate student results against their peers from other non-ARL libraries participating in the 2004 LibQUAL+TM survey. Lastly, categorizing and carefully considering survey comments enriched the quantitative data by adding context to the numbers.