Background The efficacy of 2% lignocaine is reduced in a hot tooth. Local aesthetic agents can be preheated and buffered to increase their effectiveness. The present investigation was carried out due to limited information concerning adult patients with symptomatic irreversible pulpitis in mandibular teeth. Methods A total of 252 individuals were included in the clinical trial in accordance with the selection criteria only after clinical study was registered with the Clinical Trial Registry of India (CTRI/2020/09/027796). Scores on the visual analog scale (VAS) and electric pulp test (EPT) on a 1–10 scale were recorded prior to the commencement of therapy. In this double-blinded study, patients were randomly divided by a co-investigator using computer randomisation (www.randomizer.org) into three groups, group A: inferior alveolar nerve blocks (IANB) with 2% lignocaine preheated at 42 °C (injected at 37 °C) (N = 84), group B: IANB of 2% lignocaine buffered with 0.18 ml of 8.4% sodium bicarbonate (N = 80) and group C: 2% lignocaine (N = 88). Excluding the dropouts of individuals (n = 11), wherein the anaesthesia failed, a total of 241 people were finally assessed 15 minutes after profound anaesthesia, endodontic access, and intraoperative pain were quantified using VAS. Pain on injection for all three groups was recorded immediately after IANB with VAS. The analysis was performed using one way ANOVA with Tukey’s post hoc test and Paired T-Test using SPSS version 21. Results Preheated, Buffered, and conventional 2% lignocaine showed statistically significant reduction in intraoperative pain (P < 0.001) compared to pre-operative but on inter-group comparison preheated and buffered showed highly significant pain reduction compared with conventional 2% lignocaine (P < 0.001). Conclusions Warm and buffered local anaesthetic (LA) were effective in reducing intraoperative discomfort than conventional LA. Preheated local anesthetics caused the least pain, followed by buffered local anesthetics, while conventional local anesthetics caused the most pain.
Aims: Microbiologic evaluation of cotton, polytetrafluoroethylene (PTFE) tape, and foam as an endodontic spacer material in permanent premolars and molars – an ex vivo study. Subjects and Methods: After ethical approval, 72 patients who signed the informed consent form participated in the study. Following access opening and biomechanical preparation, the teeth were randomly assigned to cotton (n = 24), PTFE tape (n = 24), and foam group (n = 24). Samples obtained from the access cavity at baseline (sample one – S1) and after seven days (sample two – S2) were checked for an increase in the microbial load. They were placed on brain-heart infusion agar plates, incubated aerobically for 48 h, and the colony-forming units were calculated. Statistical Analysis: One-way analysis of variance and Tukey's post hoc test were used and a P < 0.05 was considered statistically significant. Results: There was a statistically significant difference in all the three groups concerning baseline and after Seven-day mean values. An intergroup comparison revealed a statistically significant difference in the mean difference values between the cotton and PTFE tape group. Whereas, there was no statistically significant difference in the mean difference values between the cotton and foam and PTFE tape and foam group. Conclusions: Within the limitations of the study, it can be stated that the PTFE tape and foam group performed better than cotton.
Introduction: Chlorhexidine is commonly used to treat dental diseases as a broad-spectrum topical anti-bacterial medication. Povidone-iodine is a water-soluble blend of molecular iodine and the solubiliser polyvinylpyrrolidone. Amsarveda (pharmaceutical company) developed a natural mouth sanitiser with liposomal curcumin. Aim: Comparative evaluation of the effect of chlorhexidine mouthwash, povidone-iodine gargle and herbal mouth sanitiser on colour stability and surface roughness of conventional nanohybrid composite. Materials and Methods: This in-vitro study was conducted in the Department of Conservative Dentistry and Endodontics at KM Shah Dental College and Hospital, Vadodara, Gujarat, India, from November 2020 to June 2021. Total 60 extracted human permanent maxillary premolar teeth were selected. Class V restorations were performed on the extracted teeth with nanohybrid composite resin. The samples were divided into three groups by computer randomisation. The three test solution groups (n=20 each) ie., Group A- chlorhexidine 0.2% mouthwash, Group B has povidone-iodine (2%), Group C- herbal mouth sanitiser. The colour change and surface roughness of all the samples were measured before and 15 days after immersion into the test solutions. The data was collected and statistically analysed using one-way analysis of variance and Tukey’s post-hoc test. Results: The ΔE values for all three groups show a statistically significant difference (p-value <0.001). The mean baseline and after 15 days values for surface roughness in groups A and B showed a statistically significant difference (p-value <0.001). Whereas, no statistically significant difference in Group C (p-value=0.654). Conclusion: Based on the results of the present study, it can be stated that the povidone-iodine gargle showed more surface roughness and colour change of conventional nanohybrid composite followed by chlorhexidine mouthwash and herbal mouth sanitiser.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.