Salmonella enterica serovars typhi is a contributing typhoid agent, leading to untreatable infections based upon the rising prevalence of antimicrobial resistance in the said agent. Consequently, the main concern of the health service providers to treat expansively drug-resistant (XDR) enteric fever has been dependent on the only remaining oral drug, Azithromycin, for creating emerging resistance against it. Therefore, a cross-sectional descriptive study was conducted in the Microbiology Department of Rajshahi Medical College, Rajshahi, to identify Salmonella species by Fastidious Antibiotic Neutralization (FAN) method in suspected enteric fever cases along with its antimicrobial susceptibility pattern and molecular detection of Azithromycin resistant R717Q gene. Samples were collected purposively. Regarding the population's age distribution, out of 127 specimens, the predominant 37(29.1%) were found within the age group of 35-44 years. Automated blood culture was found positive in 64(50.39%) population; out of them, Salmonella spp were 38(59.37%) of the population. Among them 29(76.31%) have travel history, took street food 25(65.7%), used tap water for drinking 21(55.2%) and had kancha latrine 24(63.1%). It was found that 18.43% were sensitive and 81.57% resistant to Azithromycin. Azithromycin-resistant Salmonella spp. were detected in 31(81.57%), and among Azithromycin resistant R717Q gene was identified in 9(29.03%). The azithromycin-resistant R717Q gene was identified by conventional PCR. Because of its oral course of administration, Azithromycin is considered the widely used drug in Bangladesh, which is used once on a dose basis a day. In order to contribute to the development of this drug resistance, there could be many reasons, and among them there are the availability over the counter and the imperfectly done treatment. Thus, this study would be helpful to formulate a regional hospital empirical therapy by antimicrobial sensitivity and resistance pattern of the gene for Azithromycin resistance in Rajshahi Medical College Hospital. TAJ 2022; 35: No-2: 67-73
Background: Urinary tract infections (UTI), which are caused by the presence and growth of microorganisms in the urinary tract, are perhaps the single commonest bacterial infections of mankind. Urinary tract infection is a most common infectious disease after respiratory tract infection in community practice. Aim of the study: The aim of this study is to assess the drug resistance pattern of the isolated organism while treating UTIs. Material & Methods: This was a prospective study carried out in the Molecular Biology Laboratory, Institute of Biological Sciences, University of Rajshahi, Bangladesh during the period of July 2008 to June 2011. In the planning phase, we estimated a total sample size of 750 cases. The study population comprised of four hundred fifty (450) female patients clinically suspected of having UTI aged between 15-45 years attending the OPDs or admitted to
Introduction: Every day, nurses experience a great deal of stress. They face problems at work, people relying on them for their care, and also tons of responsibilities piling up at home. Psychological stress is common in hospital ward and associated with depression. Only few studies are done concerning mental health of Nurses in Bangladesh. The study was carried out with a view to find out the prevalence of depression among nurses at Mental Hospital, Pabna, Bangladesh. Materials & Methods: A cross sectional, questionnaire-based survey was carried out among the 125 nurses of Mental Hospital, Pabna. The studywas conducted between January to February 2019. The depression levels were assessed using Zung depression scale. Nurses were asked to complete the questionnaire and then the depression levels calculated. Result: The overall prevalence of depression among the nurses was 4.13 percent. The prevalence of depression was 4.5 percent among female nurses versus 2.94 percent in male nurses. Conclusion: The prevalence of depression is seen especially innurses. So, attempts should be made to alleviate the stressors. Medicine Today 2019 Vol.31(2): 111-113
Background: The aim of the study was to assess the salivary pH in dental caries children. The study was carried out with the objective of evaluation of pH of saliva by pH scale among healthy and caries children. Materials & Methods: A hospital-based study was conducted in the Department of Microbiology of Rajshahi in collaboration with Dental unit, Rajshahi Medical College Hospital, Rajshahi for a period between January to December 2017. All the cases were purposively selected from whom salivary sample were collected to measure pH using a chair side test strip. pH paper was rolled over the saliva on slide. Compare the colour against the standard to obtain a measurement. Results: The present study suggests that there is a significant relation between salivary pH and caries. Conclusion: We hypothesize that low salivary pH are associated with a higher dental caries rate. TAJ 2020; 33(1): 31-34
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