Background: Homocysteine, fibrinogen and C-reactive protein (CRP) are three independent factors that independently and strongly predict the cardiovascular risks. Objectives: The purpose of this study was to evaluate the acute and chronic responses of these cardiovascular risk factors following physical activity in overweight healthy inactive middle-aged men. Methods: The subjects included 21 healthy inactive men that were assigned into two groups of experimental (N = 11) and control (N = 10). The exercise protocol consisted of circuit resistance exercise (one session protocol) with intensity of 35% of 1RM; endurance training protocol lasting for 12 weeks (three sessions a week) and running exercise with intensity of 75% to 85% of maximum heart rate. Blood samplings were taken in pretest and posttest. The data was used using paired and independent samples t-test were used for statistical analysis of data. Results: The results indicated that there was a significant increase in homocysteine and CRP following circuit resistance exercise (P ≤ 0.05) while no significant change was found in fibrinogen in experimental group after exercise (P > 0.05). Additionally, the levels of CRP and homocysteine were significantly decreased after three months of aerobic exercises, (P ≤ 0.05) however no significant change of fibrinogen was observed (P > 0.05). Conclusions: Although it seems that atherogenic inflammatory processes are more sensitive to exercise than coagulatory processes in inactive middle-aged men, more researches are needed for crucial decisions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.