BACKGROUND Pterygium is a very common cause of visual disturbance and is treatable surgically. It is treatable by conjunctival autograft. The autograft can be sutured or can be fixed with glue or autoserum. In this study, we have compared the procedure of suturing of conjunctival autograft and sutureless autoserum procedure after the excision of pterygium. MATERIALS AND METHODS We have studied 100 patients of primary pterygium attending the outpatient department of tertiary care centre for treatment of primary pterygium, during the period from November 2015 to October 2017 with the approval of ethical committee of Katuri Medical College, Guntur. We have allocated these patients in to two groups. Group I patients numbering 50 underwent pterygium excision with limbal conjunctival autograft and the auto graft was secured with autologous serum. Group 2 patients numbering 50 had conjunctival autograft secured by sutures. Patients were examined on the first postoperative day and at the end of 1st week, 6th week and 12th week post operatively. RESULTS Eighty percent of the patients in both groups were in the age group of 31 to 60. 78% of patients of pterygium are females. Nearly half of the patients had Grade T2 Pterygium. Most of the patients in both the groups had wide based pterygia. The mean duration of surgery in Group 2 (28.34 minutes) was found to be longer than that of Group 1 (18.68 minutes), Pain and foreign body sensation were lesser throughout the follow-up period and disappeared more rapidly in Group 1 compared to Group 2, and the difference was found to be statistically significant (p<0.001). There was no difference in graft oedema between the two groups (p>0.05). There was no evidence of recurrence in both the groups, during the period of follow-up. CONCLUSION Both conjunctival autografting with autologous serum and with sutures are safe with low recurrence but autografting group has lesser symptoms and duration of surgery is shorter with autologous serum group. Graft displacement and graft retraction were equal in both the groups
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