A variety of 3,4‐disubstituted pyrroles and benzo[f]indole‐4,9‐diones have been selectively synthesized from readily available aromatic aldehydes, 1,3‐Indanedione and tosylmethyl isocyanide (TosMIC) by a one‐pot procedure in high yields. This methodology features operationally simple, practical with broad substrate scope and usage of easy to handle reagents. The one‐pot sequential reactions proposed to proceeds through a tandem in situ generated chalcones and [3+2]‐cycloaddition/ring cleavage or expansion process.
A cascade synthetic strategy for the direct synthesis of dibenzo[a,d]cycloheptanoids and dibenz[a,c]anthracene-9,14-dione derivatives from aryne precursors has been developed.
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