TP53, encoding p53, is one of the most famous tumor suppressor genes. The majority of human cancers demonstrate the inactivation of the p53 pathway. Mutant p53 not only, no longer, functions as a tumor suppressor but can also exert tumor-promoting effects. The basic function of p53 is to respond to cellular stress. We here in this review article discusses about the recent advances in p53 research, mainly focusing on apoptosis and therapy for human cancer. Hence, this review aims to update the current related articles and provide a further understanding about such molecular changes relevant to trigger imbalances in the regulation of apoptosis in cancer.
Pollution has been the major problem since decades, destructing our environment and resources. Among all types of pollutions, heavy metal pollution is causing major threat to the biosphere. It is mainly resulted due to the release of Industrial wastes into the atmosphere. Industries follow various chemical procedures to remove harmful pollutants from the industrial effluents associated with various disadvantages as a result many eco-friendly techniques have come into light keeping due to the disadvantages of the chemical techniques. Biosorption of heavy metals by microbial cells has been recognized as a potential alternative to existing technologies for recovery of heavy metals from industrial waste. Present review focuses on the biosorption of different metals by different means which lead to the eco friendly clean up of the environment without causing any damage as such to the surroundings/ without the release of chemicals into the atmosphere, this article mainly deals with the biosorption of Fe, Cr (VI),U, Pb, Cu2+, Cd(II), Mn, Zn, Ni, Lanthanides, Ni and the role of this technique in cleaning up of the environment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.