A rapid and sensitive ultrasound-assisted temperature-controlled ionic liquid (IL) dispersive liquid-phase microextraction (UTILDLPME) combined with reversed-phase liquid chromatography-ultraviolet (RPLC-UV) was developed for the determination of five organophosphorus pesticides (OPPs; azinphos-methyl, chloropyriphos, parathion-methyl, diazinon, and phosalone) in water samples. Parameters including IL type, IL volume, ionic strength, sonication time, heating/cooling temperature, centrifugal time, and speed were investigated. The extraction procedure was induced by the formation of cloudy solution, which was composed of 75 L of 1-butyl-3-methylimidazolium hexafluorophosphate ([C4MIM]PF 6 ) dispersed entirely into 5 mL sample solution with the assistance of ultrasound for 3 min and temperature at 40°C. Under optimal conditions, linearity of the five OPPs was obtained in the range of 0.09-200 ng/mL with correlation coefficients of 0.998 or more. Limits of detection and limits of quantitation ranged from 0.01 to 0.1 ng/mL and from 0.05 to 0.4 ng/mL, respectively. Compared with conventional microextraction techniques, the proposed UTILDLPME exhibited the highest extraction efficiency ranging between 90 and 98% for targeted OPPs. Furthermore, the proposed UTILDLPME/RPLC was successfully applied to different water samples (tap, well, and lake water) showing relative recoveries ranging from 96.9 to 103.2%. Therefore, UTILDLPME/RPLC-UV could be a simple, rapid, sensitive, and efficient routine technique for determination of OPPs in water.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.