All tested bacteria and plant extracts proved larvicidal activity against third instar larvae of both mosquitoes Culex pipiens and Aedes caspius .Bacillus sphaericus, indigenous strain (dammam) showed higher activity against Cx. pipiens larvae, with LC50 = 0.35x10-7 ppm. Than to Ae. caspius (LC50= 4.5x10-7 ppm) .Bacillus thuringiensis H-14 (Bactimos) has higher toxicity against Ae. caspius, followed by Cx. pipiens (LC50=8.0x10-7 and 1.4x10-6 ppm respectively. Both mosquito larvae were susceptible to all tested native plant extracts,
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