Abstract. The amalgamation of polymer and pharmaceutical sciences led to the introduction of polymer in the design and development of drug delivery systems. Polymeric delivery systems are mainly intended to achieve controlled or sustained drug delivery. Polysaccharides fabricated into hydrophilic matrices remain popular biomaterials for controlled-release dosage forms and the most abundant naturally occurring biopolymer is cellulose; so hdroxypropylmethyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose and hydroxyethyl cellulose can be used for production of time controlled delivery systems. Additionally microcrystalline cellulose, sodium carboxymethyl cellulose, hydroxypropylmethyl cellulose, hydroxyethyl cellulose as well as hydroxypropyl cellulose are used to coat tablets. Cellulose acetate phthalate and hydroxymethyl cellulose phthalate are also used for enteric coating of tablets. Targeting of drugs to the colon following oral administration has also been accomplished by using polysaccharides such as hdroxypropylmethyl cellulose and hydroxypropyl cellulose in hydrated form; also they act as binders that swell when hydrated by gastric media and delay absorption. This paper assembles the current knowledge on the structure and chemistry of cellulose, and in the development of innovative cellulose esters and ethers for pharmaceuticals.

Particulate matter (PM) pollution is a significant burden on global economies and public health. Most present air filters are heavy, bulky, and nontransparent and typically have inevitable compromise between removal efficiency and air permeability. We report a scalable strategy to create ultralight, thin, rubbery, self-assembled nanoarchitectured networks (nanonetworks) with high-efficiency and transparency (ULTRA NET) as air filters using capacitive-like electronetting technology. By controlling the ejection, deformation, and phase separation of charged droplets from a Taylor cone, our approach allows continuously welded two-dimensional nanonetworks (∼20 nm fiber diameter) to assemble into filters on a large scale. The resulting ULTRA NET filters exhibit integrated properties of desirable pore structure yet maintaining strikingly low thickness (∼350 nm) and free-standing capability, 99.98% removal efficiency, and <0.07% of atmosphere pressure for PM0.3 filtration at ∼85.6% transmittance, which enable them to serve as a multifunctional filter against PMs either in rigid solid or in soft oil forms and even biohazard pathogens. This work should serve as a source of inspiration for the design and development of high-performance fibrous materials for various filtration and separation applications.

Textiles with excellent moisture transport characteristics play key role in regulating comfort of the body, and use of color in textiles helps in developing aesthetically pleasing apparels. Herein, we report an aesthetically pleasing and breathable dual-layer cellulose acetate (CA) based nanofibrous membranes with exceptional directional moisture transport performance. The outer layer was synthesized by subjecting CA nanofibers to hydrolysis and reactive dyeing processes, which converted moderately hydrophobic CA nanofibers into uniformly colored superhydrophilic CA nanofibers with an excellent wettability. In addition to excellent wettability and superhydrophilic nature, dyed CA (DCA) nanofibers also offered high color yield and dye fixation as well as considerable colorfastness performance against washing and light, thus, were used as the outer layer. However, pristine CA nanofibers were chosen as the inner layer for their moderate hydrophobicity. The subsequent CA/DCA nanofiber membrane produced a high wettability gradient, which facilitated directional moisture transport from CA to DCA layers. The resultant dual-layer nanofiber membranes offered a high color yield of 16.33 with ∼82% dye fixation, excellent accumulative one-way transport capacity (919%), remarkable overall moisture management capacity (0.89), and reasonably high water vapor transport rate (12.11 kg d m), suggesting them to be a potential substrate for fast sweat-release applications.

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