The pCLE is a promising method for differentiating between nondysplastic, precancerous, and cancerous lesions of the head and neck.

This pilot study demonstrated a significant decrease in serum IFN-γ, IL-13, and MIP-1β levels and a significant elevation of serum IP-10 concentration in patients with HNSCC, irrespective of primary tumor site. If validated in larger, independent studies, these serum biomarkers may be useful in the diagnosis and treatment of HNSCC. In the future, a defined, multianalyte screening panel could facilitate early diagnosis of HNSCC, allowing for earlier treatment and thereby reducing patient mortality.

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HighlightsTraumatic abdominal wall hernias (TAWHs) and traumatic abdominal aortic injuries (TAAIs) are complications of severe blunt trauma.CT is a sensitive imaging modality to detect TAWHs.As only severe TAAI will have positive physical exam findings, imaging techniques, surgical exploration, or on-table angiogram may aid in diagnosis.

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