BackgroundChronic Urticaria (CU) is a group of diseases that share a distinct skin reaction pattern. Triggering of urticaria by infections has been discussed for many years but the exact role and pathogenesis of mast cell activation by infectious processes is unclear. The remission of annoying spontaneous chronic urticaria has been reported after successful treatment of persistent infections.ObjectiveTo describe the infections found in chronic urticaria patients in our service, by performing a complete medical history, physical examination, laboratory studies and cultures.MethodsUniverse: Consecutive patients with chronic urticaria, with a detailed history, physical examination, laboratory studies underwent clinical viral panel, cultures, biopsy for detection of H. Pylori.ResultsA total of 50 patients, mostly women 82% and 18% men, mean age 41 years. 42% of the total population had salmonella, proteus infection in 20% and 8% brucellosis. Crossed with urinary tract infection 6% of the population. Five patients had positive stool in 3 patients Endolimax nana was isolated and 2 patients reported Giardia lamblia, 5 patients (10%) women had undergone cervicovaginitis 2 of them infected with S. haemolyticus, the rest was cultivated E. faecalis, and T. Gardenella vaginalis, respectively. Was isolated in 2 patients and one patient H.pilory HCV infection.ConclusionsInfections may play a causal role of UC in some cases. Were identified in 42% of cases and gastrointestinal infections by most common cause Salmonellosis. As for genitourinary tract infections, intestinal parasites, Helicobacter pylori, were treated appropriately with antibiotic therapy, found a successful resolution of urticaria mainly in patients infected with Helicobacter pylori. There is growing evidence that persistent infections in chronic urticaria are important triggers, particularly in the case of infection by Helicobacter pylori, so If an infection is identified, it should be appropriately treated and it should be checked whether eradication has been achieved.
BackgroundChronic urticaria (CU) is a disease defined by the presence of wheals and itching for more than 6 weeks. Depending on its severity, it may impair the patients’ quality of life (QOL). The questionnaire Cu-Q2oL designed by Dr. Walter Canonica's group, specifically evaluates quality of life in patients with chronic urticaria (CU-Q2oL); in Spanish it has been validated by Dr. Valero, et al.ObjectiveWe aimed to investigate if there is an association between severity of chronic urticaria and quality of life of patients in our service, using the questionnaires: CU-Q2oL and urticaria activity score (UAS).MethodsUniverse: Consecutive patients with chronic urticaria who answered the questionnaires CUQ2OL and UAS. Diagnosis of CU was based on a detailed history, physical examination, laboratory studies and autologous serum skin test (ASST) for Autoimmune Urticaria (UCAI). Spearman's Rho correlation coefficient was calculated between Severity (UAS) and Quality of Life (CUQ2OL). Comparisons between groups were performed using chi square and One-way ANOVA.Results50 patients, (82% women, mean age 41 years) were included. The largest etiology group was Autoimmune: 60% of cases; A direct linear relationship between the severity of and quality of life was found to be statistically significant (r2 0.511, P < 0.0001). A greater severity was generally reported in the autoimmune group.ConclusionsPatients with more severe urticaria, particularly with major complaints of itching and sleep loss, have a lower quality of life, especially those patients with autoimmune urticaria. We found a good correlation between both questionnaires, so in the future clinicians may anticipate that patients diagnosed with moderate or severe chronic urticaria might have a considerable drop in their quality of life, and therefore their management and follow-up should be viewed holistically.
This study, which is part of a larger inquiry that examined the stories of first generation Latina Millennials as they described their journeys in academia through testimonios, focuses on the academic support they received navigating the educational spaces at City University (pseudonym), a Hispanic-serving institution in California. The goal is to share the participants' testimonios or first person narratives to highlight the academic support they received as they pursued advanced degrees. In general, academic support at City University was defined by the participants in the following subthemes: departments, graduate programs, faculty and staff, cohort, and research interests.
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