Infectious endocarditis is an infrequent pathology but with a very significant morbidity and mortality context. The MostCommon responsible germs are streptococci and staphylococci.Neisseria is a strain of bacteria characterized by several subgroups such as gram-negative diplococci which are present in the respiratory tract and which are generally harmless and other gram-negative bacteria such as Neisseria gonorrhoeae which are known to be pathogens involved in several pathologies.We report a case of infectious endocarditis in 37-year-old patient with mitral valve replacement who presented a prolonged febrile syndrome with discovery on transesophageal echocardiography of vegetation and blood cultures of an SP Neisseria.
Von willbrand syndrome remains a rare pathology. Its etiologies and clinical manifestations are varied. This syndrome can be inherited or acquired. The acquired form is associated with various pathologies (Gastric, mechanical support system…) including cardiovascular diseases such as aortic stenosis, HCM, and Mitral regurgitation. Nevertheless, the association of acquired Willebrand syndrome with coronary pathology remains a rare association. In this literature review, we have made a review of the various articles addressing this subject. The management of ACS in patients with AvWS follows that of normal patients in terms of interventional procedure, however therapeutic drug management remains delicate given the hemorrhagic risk that these drugs present. The use of DAPT and heparin is possible while thrombolysis remains at very high risk for the patient. The use of desmopressin can be done with caution and also factor VIII and vWF concentrates have their place to reduce the risk of bleeding. Overall, the collaboration of the cardiologist and hematologist remains essential for better management of these patients.
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