Duck plague is an economically devastating viral disease prevalent in ducks which causes massive loss of duck populations annually. High morbidity and mortality are characteristic of the infection and outbreaks. Duck plague is reported from time to time from different parts of our country including Assam. The infected ducks manifest clinical signs like photophobia, partially or completely closing of eyelids, excessive thirst, nasal discharge, anorexia, drooped plumage, ataxia, diarrhea with soiled vents along with tremors in the head, neck and body. Present study was aimed to evaluate the deleterious effects of duck plague virus on liver and kidney condition by estimating liver and kidney specific biomarkers from indigenous ducks, namely Pati, Nageswari and Cinahanh of Assam from different agroclimatic zones. Study revealed significant increase of AST, ALT, ALP, uric acid and creatinine which is indicative of disruption of healthy function of liver and Kidney due to duck plague virus infection.
West Nile virus (WNV) is a zoonotic, emerging mosquito-borne virus which can cause severe disease in the form of encephalitis and acute flaccid paralysis in humans. In Assam, northeast India, arboviruses seem to be re-emerging, however, WNV has been little studied. The present investigation was carried out from April, 2018 to March, 2019 to study sero-positivity of WNV in chicken in urban and peri-urban areas of Guwahati, the capital city of Assam. Four urban and four peri-urban areas of Guwahati were selected. A total of 864 chicken serum samples (72 samples per month) were screened by ELISA and further confirmed by haemagglutination inhibition (HI), which revealed that 3.13% of the chickens had been exposed to WNV, with 0.69% sero-positivity in urban areas compared to 5.56% in peri-urban. Peak sero-prevalence of WNV were reported during the month of July and August with 8.33% each with lowest sero-prevalence being recorded in November (1.39%) and no sero-positive birds from December to April. These results indicate that WNV is one of the actively circulating flaviviruses in Assam, and human febrile and encephalitic cases should be screened for the disease.
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