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PurposeCollecting duct carcinoma (CDC) of the kidney is an aggressive disease with a poor prognosis, accountings for less than 1% of all renal cancers. To date, no standard therapy for CDC has been established. The aim of this study is an investigation of clinicopathologic findings of CDC and correlation of the disease status with a prognosis.Materials and MethodsFrom 1996 to 2009, 35 patients with CDC were treated at eight medical centers. The diagnosis of CDC was made based on nephrectomy in 27 cases and renal biopsy in eight cases.ResultsMedian PFS and OS for all patients were 5.8 months (95% CI 3.5 to 9.2) and 54.4 months (95% CI 0 to 109.2), respectively. The OS of patients with Stages I-III was 69.9 months (95% CI 54.0 to 85.8), while that of patients with Stage IV was 8.6 months (95% CI 0 to 23.3), which showed a statistically significant difference (p=0.01). In addition, among patients with Stage IV, the OS of patients who received a palliative treatment (immunotherapy, chemotherapy, or targeted therapy) was 18.4 months, which was higher than the OS of patients without treatment of 4.5 months.ConclusionCDC is a highly aggressive form of renal cell carcinoma. Despite most of the treatments, PFS and OS were short, however, there were some long-term survivors, therefore, conduct of additional research on the predictive markers of the several clinical, pathological differences and their treatments will be necessary.

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Metal marking and scratching are related to surface roughness, hardness and toughness of glaze. To improve the glaze properties, frits were added in the traditional celadon glaze and reducing firing atmosphere was controlled. Surface roughness of celadon glaze was decreased with increasing the reducing agent content (LPG flowing rate) and increasing the frits content. Though hardness of glaze without frit was increased with increasing the reducing agent content, hardness of glaze with frit was not changed extremely with increasing the reducing agent content. To evaluate the metal marking and scratching resistance, wear resistance test was used with stainless steel ball. After wear test, many metal marks and wide scratching trace were observed in the traditional celadon glaze. However, a few metal mark and scratch were observed in the celadon glaze with frit. The friction coefficient of glaze in the wear test was strongly depended on the frit contents.