A two-year retrospective study between 1996 and 1997 was carried out at the University of Nigeria Teaching Hospital, Enugu, to determine the patterns of intestinal helminth infection. A total of 13385 stool samples were examined using the direct smear technique. Some samples were also examined using the formal ether concentration method when direct smears were negative. Hookworm, Ascaris, Trichuris and Strongyloides were the most common helminths. Hookworm was the most prevalent (14.3%). Generally infection was most prevalent in adolescents aged 12-17 years, except for ascariasis, where the 6-11 year age group had the highest prevalence. Multiple infections were common (12.6%), with the most common combination being hookworm and ascariasis. To reduce the prevalence of various helminth infections the level of environmental sanitation, socioeconomic status of the populace and water supply should be improved.

Blood safety is a major issue of global concern in transfusion medicine especially in developing countries, where national blood transfusion policies and services as well as financial resources are lacking or inadequate. Transfusion-transmitted malaria is a potential health hazard but is often neglected in many malarious areas. Malaria infection among blood donors in Onitsha urban, Southeast Nigeria was studied between August and October 2008. Venous blood of donors was screened for malaria parasites using Giemsa-stained thick and thin blood films. The ABO and Rhesus phenotypes were classified using a haemaglutination standard test and demographic data of donors documented. Of the 410 blood donors analysed, 304 (74.1%) were infected. Plasmodium falciparium was identified in all positive cases and mixed infection with P. malariae was seen in 5(1.6%) cases. Infection significantly varied with age and not with sex and occupation (p<0.05). People with blood group O + showed significantly higher rate of infection (p<0.05). Since there is scarcity of voluntary donors in Nigeria, donor deferral done in non-malarial endemic regions cannot be practiced in Nigeria. The high prevalence of asymptomatic malaria in this area, suggests the need for careful screening of blood samples for malaria parasites. Positive samples should be indicated on the blood packs and transfusion of malaria positive blood requires the administration of curative dose of antimalarials to the patient. Commercial donors should be freely given mosquito treated bed nets and be encouraged to sleep under them.

This prospective study was carried out between July and December 2000 at the University of Nigeria Teaching Hospital (UNTH), to determine the species and prevalence of intestinal helminthes in pregnant women attending antenatal clinics. A total of 161 stool samples were collected from the women. The samples were examined by the kato thick smear technique. For each stool sample, two kato slides were made and the average of the total number of eggs was taken. The prevalence of helminthic infection was 11.8% with only Ascaris lumbricoides (8.7%) and Trichuris trichuria (3.1%) being detected. The intensity of infection was generally high with a geometric mean intensity of 50.1 eggs per gm of faeces. About 11.8% of cases were multiple infections. There was no significant difference between the mean haemoglobim levels in both the infected pregnant women and the non-infected pregnant women. The poor socioeconomic status of the women coupled with poor environmental sanitation and lack of clean portable water supply contributed to the high prevalence of these parasites.

The pattern of transmission of human schistosomiasis was studied in Amagunze Village, eastern Nigeria, during 1986–1987. The prevalence of Schistosoma haematobium in 119 schoolboys aged 5–12 years was 79%. The geometric mean of intensity of infection was 49 eggs/10 ml urine and the frequency of visible haematuria was 25·2%. No S. mansoni infections were demonstrated. A marked seasonality in population density of Bulinus truncatus, B. forskalii and Biomphalaria pfeifferi was demonstrated with reduced densities during the late rainy and early dry seasons. Schistosoma sp. infected B. truncatus were found in the late dry and early rainy seasons in 2 out of 7 major human water contact sites studied. Seasonality and focality of transmission of S. haematobium and its high endemicity in the area were thus demonstrated.

The mosquito fauna of Museum and Zoological Garden Complex (JZC), a major tourist attraction in Jos Metropolis of Nigeria, was studied The choice of the complex was out of public health curiosity. A total of 627 mosquitoes comprising 4 genera, Aedes, Culex, Coquilletidia and Eretmapodites, and 9 species were caught n two d fferent study trips. Five species, namely, Aedes aegypti, A. africanus, A. vittatus, Culex quinquefasciatus and Eretmapodites chrysogaster, caught by human bait method are known variously to be involved in the transmission of yellow fever and other viral diseases. Culex quinquefasciatus had the highest frequency followed by Aedes aegypti. Simpson's dominance and Shannon-Wiener diversity indices of 0.4942 and 0.4550 were respect vely recorded for the whole mosquitoes sampled by the human bait method. C. quinqefasciatus was the most frequent species with diversity values of 0.4444 (Simpson's) and 0.1174 (Shannon-Wiener), followed by A. aegypti with 0 0455 (Simpson's) and 0.1431 (Shannon-Wiener). Ecological statistics demonstrated a highly significant dif erence in diversity between samples in March, during the dry season, and June in the rainy season (P < 0.001). The presence of man-biting mosquitoes in JZC constitutes apparent public health danger and calls for regular surveillance and control operations on such disease vectors in the complex.