The male factor is the cause of infertility in 40 % of cases. This study is dedicated to the efficiency assessment of ICSI
and PICSI techniques and the determination of indications of these methods. There are some relative indications for ICSI
in clinical practice: advanced reproductive age of patients, a small number of obtained oocytes, prolonged infertility,
repeated attempts of in vitro fertilization. However, normal sperm values are registered in 71.3 % of cases. PICSI method
is more preferable at high level of DNA fragmentation and associated changes in sperm indicators. Nevertheless, the
pregnancy rate after these methods was comparable – 19.3 % and 19.7 % respectively. The results indicate that the ICSI
and PICSI methods do not have a negative impact on the quality of the embryos and do not increase the pregnancy rate.
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