Thermography is the method of noninvasive registration of visible image of own infrared radiation of the human body surface by special devices. The results of filtration bleb investigation, carried out by thermography method are presented in patients with open angle glaucoma in different terms after glaucoma surgery. Purpose. To execute an investigation of a filtration bleb in patients with open angle glaucoma in different terms after glaucoma surgery by method of thermography. Material and methods. 35 patients (35 eyes) with open angle glaucoma were examined after 1, 7 days, after 1-3-6 months after minimally invasive sinustrabeculectomy. Authors used thermal imaging Тesto 875-2i with SuperResolution technology and telephoto lens 9° x 7°. The bleb area and temperature were evaluated With IRSoft and Universal Desktop Ruler programmes. Intraocular pressure (corneal compensated) (IOPcc) was measured with Ocular Response Analyzer®, ORA. Investigation protocol included 2 groups. Group №1 - 15 patients (15 eyes) with moderate glaucoma. Group №2 – 20 patients (20 eyes) with advanced glaucoma. All patients went through glaucoma surgery, microinvasive sinustrabeculectomy. Management and recurrent examinations were carried out in 1 and 7 day after glaucoma surgery; then in 1, 3 and 6 months after surgery. Results. The IOP level was credibly lowered in all patients in all terms of management in comparison with the baseline IOP level. High statistical correlation was determined in patients of 1 group between IOPcc and the index of temperature difference (between filtering bleb and surrounding conjunctiva temperatures), correlation coefficient >0,7, in all management terms after surgery (in 1, 3, 6 months). In 2 group there was determined statistical correlation between IOPcc and index of temperature difference between filtering bleb and surrounding conjunctiva temperatures (Δ Тsc - Тfb) in 1 week, in 1 and 3 months after surgery. The same correlation coefficient was determined between filtering bleb temperature and Δ Тsc- Тfb in 6 months after surgery. Conclusion. Thermography is a safe and noninvasive method, that credibly detects temperature elevation in surgery zone, indicates IOP level raise and can predict starting of filtering bleb scarring. This method defines the necessity of needling procedure execution in different terms after surgery treatment and allows to control its effectiveness. Key words: open angle glaucoma, filtering bleb, scarring, thermography, corneal compensated intraocular pressure, Ocular Response Analyzer.
Uncontrolled administration and prolonged use of antihypertensive drugs with preservatives often leads not only to subjectively poor tolerance of treatment, but also to a deterioration in the results of subsequent surgery, if required. The manifestations of dry eye syndrome and its aggravation as a result of such drops use can lead the patients to refuse therapy and worsening the prognosis. The manifestations of dry syndrome are often detected before any hypotensive therapy begins, since the functions of secretory cells change with age and there is always the influence of adverse environmental factors. It is necessary to examine the condition of the anterior surface of the eye to resolve the issue of the need to prescribe drugs without preservatives for all patients before the appointment of antihypertensive therapy. However, sometimes it is not possible due to lack of time or equipment. Therefore, it is important to study the condition of the anterior eye surface in patients with newly diagnosed glaucoma before and during treatment with nonpreservative forms of antihypertensive drugs in order to determine the necessity of the first prescription of non-preservative forms of antihypertensive drops to further interpolate its results into practical recommendations. This study revealed that drug treatment of patients with newly diagnosed glaucoma with the drug Timolol-POS® β-blocker on a non-preservative basis along with IOP compensation improves both subjective and objective indicators of the condition of the anterior surface of the eye with maximum effect after 3 months of treatment. This conclusion suggests the importance of the primary appointment for such patients with instillation drops on a preservative basis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.