The paper considers comparing the anti-inflammatory action of the food concentrate “Enoant” and a classical antioxidant – resveratrol in the doses of 20 mg/kg in the model of an acute exudative inflammatory of animals. It was proved that resveratrol had the most anti-inflammatory action; this was manifested by a considerable decrease of the increase rate of the animal paw’s size in the formalin test after 7 and 14 days of taking the antioxidant. The food concentrate “Enoant” demonstrated anti-inflammatory properties after 7 days of taking the antioxidant; this was manifested by the increase of the animal paw’s size in the formalin test, however 14 days later a moderate anti-inflammatory reaction was registered, this was manifested by the decrease of the increase rate of the animal paw’s size in the formalin test..
The aim. To assess the effect of glucose-electrolyte composition with plant extracts having antioxidant activity on the hemodynamic parameters of vertebrobasilar system during the incrementally increasing submaximal exercise test.Materials and methods. The study included 12 athletes (6 candidates for master of sports and 6 masters of sports) aged 18–22, who have been engaged in orienteering for 10 years and more. Time of aerobic exercise – 2 hours a day, five days a week. The study subjects performed an incrementally increasing submaximal exercise test and also submaximal exercise test with the preventive intake of a glucose-electrolyte composition with plant extracts having antioxidant properties. To assess the hemodynamic parameters in all study subjects we used Doppler ultrasound of the cerebral vessels, evaluating vertebrobasilar system blood flow, exercise gas test in the modification of hypo- and hyperventilation, and also positional test.Results. A single intake of glucose-electrolyte drink under conditions of incrementally increasing exercise test contributed to the manifestation of a homeostatic effect in hemodynamic parameters of the vertebrobasilar arteries. It is evidenced by the approximation to the pre-exercise level of maximum systolic velocity and average blood velocity in the breath-holding test, of the diastolic blood velocity in the hyperventilation test, and of the pulsatility index in the torsion test, as compared to the isolated submaximal exercise test which caused the change in both velocity indicators and calculated indices during the functional tests.The article considers the main mechanisms underlying the change in arterial hemodynamic parameters caused by incrementally increasing load, as well as describes the proposed mechanisms arising from the combined effect of an incrementally increasing load and the intake of a glucose-electrolyte composition with plant extracts having antioxidant activity.Conclusion. It was shown that using glucose-electrolyte drink contributed to the restoration of hemodynamic parameters of the vertebrobasilar arteries after an incrementally increasing submaximal exercise test.
The tissue microhemodynamics plays a significant role in a tissue homeostasis. Any pathological processes were changes in functioning of microhemodynamics. This is causes is significant interesting to safe methods for its correction. One of such methods is exposure to low-intensity electromagnetic radiation of the millimeter (MM) range, which has pronounced of biological activity. The aim of the work was to identify changes in the processes of microcirculation in human skin when exposed to a low-intensity EMR MM range (wavelength - 7.1 mm; power flux density - 0.1 mW/cm2). The study was conducted on 40 volunteer girls aged 18-20 years. The exposure of low-intensity MM radiation was carried out daily for 10 days with an exposure of 30 minutes on the area of biologically active area GI-4. Microcirculation indices were recorded by laser Doppler flowmetry both in the area of influence of MM radiation (contact point of registration) and in the symmetrical effect of the area (distant point) to detect local and systemic changes in tissue blood flow under the action of this physical factor. The results of the study revealed for the first time that when exposed to low-intensity MM radiation, local changes in tissue blood flow in the contact point area were observed, manifested in changes in myogenic and endothelial oscillatory activity, starting from the first sessions of exposure, which indicates a decrease in peripheral resistance of precapillary sphincters and an increase in secretory activity of microvascular endothelium; changes in neurogenic oscillations-starting from the third session, which is accompanied by a decrease in arteriolar resistance; changes in pulse fluctuations - during the last tenth session of exposure, which is an indication of an increase in arteriolar blood filling. These changes were maintained during the entire period of exposure to this physical factor. Systemic changes in microcirculation parameters at a distant symmetrical point during the course action of MM radiation were characterized by changes in the neurogenic oscillator component, starting from the third session of exposure, and changes in the amplitude of endothelial and pulse oscillations - during the tenth session.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.