E-learning is regarded as a mandatory teaching and learning approach in higher education worldwide. Despite its importance and popularity, several issues on its use and effectiveness still remain. Universities are facing problems oflow e-learning usage among students and even academic staffs. This study investigate students' acceptance of e-learning in university using modified TAM model consists of six constructs namely instructor characteristics, computer self-efficacy, course design, perceived usefulness, perceived ease of use and intention to use. Results shown that computer self-efficacyhas significantly effects ease of use, while perceived ease of use significantly affectsintention to use e-learning.