Aim To assess the effect of Neem versus 2.5% NaOCl as root canal irrigants on the intensity of post‐operative pain and amount of endotoxins following root canal treatment of mandibular molars with necrotic pulps. Methodology This parallel, prospective, double‐blinded, randomized controlled trial with allocation ratio 1:1 was conducted in the out‐patient clinic of the Endodontic Department, Faculty of Dentistry, Cairo University, Egypt. Fifty healthy patients with mandibular molars with necrotic pulps were randomly assigned into two equal groups using computer software. In the intervention group, root canals were irrigated using Neem; whilst 2.5% NaOCl was used in the control group. A standard root canal treatment was performed in two visits using ProTaper Next rotary files, with no intracanal medication. Pain intensity was assessed using a numerical rating scale (NRS) 6, 12, 24 and 48 h following instrumentation and canal filling. Endotoxin samples were collected using three paper points before and after canal instrumentation and a sandwich ELISA method was used to quantify the level of endotoxins. Demographic, baseline, and outcome data were collected and analysed using chi‐square tests (for the comparisons of categorical variables), Mann–Whitney tests (for non‐normally distributed variables) and Student’s t tests (for normally distributed variables), A P‐value < 0.05 was considered to be statistically significant. Results The mean pain scores within the two groups decreased continually over time. The mean pain scores in the Neem group were lower than those in the 2.5% NaOCl group at 6, 12, 24 and 48 h following instrumentation and canal filling with no significant difference between them except at 24 h following instrumentation (P = 0.012). Both irrigants significantly reduced endotoxin levels compared to the pre‐instrumentation samples (P < 0.001) by 8% for the NaOCL group and 18% for the Neem group. Conclusion Neem and 2.5% NaOCl were not significantly different in terms of reducing the intensity of post‐operative pain during all follow‐up periods except at 24 h following instrumentation where Neem was associated with lower pain intensity. Both irrigants significantly reduced endotoxin levels but were not effective in eliminating endotoxins completely from root canals of mandibular molars with necrotic pulps.

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Great interest has been arising in the precise measurements of ambient ELF magnetic fields. Among the most convenient and cheap devices used .in measuring ELF magnetic fields are fluxmeters. In regions where field values change rapidly within sense coil dimensions, signijkant inaccuracies result in fluxmeter measurements. This paper proposes a novel approach using which local field distributions within the fluxmeter sense coil dimensions may be obtained. Theoretical details and sample simulation results of the approach are given in the paper.

Aim:The present study aimed to compare the efficacy of 4% Artpharmadent anesthetic solution compared to 2% Mepecaine-L anesthetic solution in extraction of badly decayed mandibular first primary molar for infiltration in children aged from 6 to 8 years.Methodology: Twenty children with 20 badly decayed mandibular first primary molars indicated for extraction divided randomly into two equal groups (n= 10), group A received 4% Artpharmadent and group B received 2% Mepecaine-L anesthetic solution for infiltration. Intraoperative pain, the need for supplemental injection during extraction, adverse effects following the anesthetic injection, and the clinical success of the treatment were evaluated for both groups.Results: Both groups showed nearly similar results regarding intraoperative pain using Wong-Baker Face Pain Scale (WBFPS), and Sound, eyes, and motor (SEM) scale, regarding the need for supplemental injection during the extraction, and the adverse effects following the anesthetic injection (non-significant difference statistically).Conclusions: Both the 4% Artpharmadent and 2% Mepecaine-L are equally effective in controlling intraoperative pain during the extraction of mandibular molars and both are safe when used in children.