The dependence of the human c-wave from the step amplitude was studied qualitatively. The maximum of the c-wave is achieved with light stimuli longer than 10 sec. After a dark period of 10 sec a fully developed c-wave appears. Also, in response to a brilliant photoflash a c-wave could be recorded. The influence of a mobile pupil on the response in the DC-ERG is demonstrated. Responses of the retinal potential to square wave and sinusoidal stimuli of different period times have been registered.
More than 60 patients with retinal vessel occlusions were examined using the electro-oculogram (EOG) ramp test. In the course of the disease a systematic disturbance of the slow oscillation of the corneoretinal potential occurred. First, the latency of the light peak increased. Then the peak decreased and was reached up to 5 min later than in the healthy eye. In the final stage the basic level dropped to about half of the normal value and light response was absent. During the next few weeks an improvement in the basic level took place, but usually this did not involve improved vision.
The "fast oscillation" of the corneoretinal potential can be precisely examined by means of cyclic light stimuli and an automatic measuring device. This new procedure is carried out during the period of adaptation as part of the usual EOG-test. Normal values and some clinical findings are presented. The fast oscillation may provide additional information when compared with EOG and ERG results.
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